This study demonstrates that nitroglycerin and ergonovine predominantly influence coronary conductance arteries whereas adenosine mainly dilates coronary resistance vessels. These findings also demonstrate that the combined use of a two-dimensional and a Doppler ultrasound transducer within one catheter assembly can provide information on the differential effects of vasoactive agents on the epicardial and microvascular coronary circulation.
Thus, these acute studies in anesthetized dogs suggest that inhibition of AT1-receptors in the coronary circulation results in vasodilator responses greater in magnitude than ACE inhibition and partly endothelium dependent. The exact role for AT1-receptors in human coronary physiology and pathology remains to be defined.
Cardiac blood cysts are rare with most cases stemming from the pediatric population. The few case reports in adults have not generated clear guidelines regarding management. The finding of a cardiac mass engenders a broad differential including primary cardiac benign tumors, malignant tumors both primary and metastatic, as well as infectious processes in addition to blood cysts. The clinical context, imaging results, and potential for complications must be taken into account when making diagnostic and treatment decisions. We present, to our knowledge, the first case of a giant cardiac blood cyst resected in an adult with a history of tuberculosis.
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