Introduction: Chronic low back pain (cLBP) patients may benefit from multimodal functional restoration programs (FRPs). The aim of this study was to analyze patients' characteristics, when oriented or not towards such a program. As cLBP is a bio-psycho-social disorder medical and social parameters were analysed. Methods:Observational cross-sectional study in six tertiary centers in France in 2017. Consecutive patients with cLBP visiting a rheumatologist or physical medicine and rehabilitation physician were included. Patients oriented or not towards a FRP were compared for demographic characteristics, duration of sick leave over the past year, self-reported physical activity >1h/week, pain, anxiety/depression (Hospital Anxiety and Depression Scale), disability (Oswestry Disease Index) and kinesiophobia (Tampa Kinesiophobia Scale). Univariate and multivariate logistic regression were performed.Results: 147 patients were analysed: mean ± standard deviation, age 48.8 ± 12.0 years, mean cLBP duration 9.1 ± 9.4 years, 88 (59.9%) women. Overall, 58 (39.5%) patients were oriented towards a FRP: these patients were younger (mean age 46.3 ± 11.2 vs 50.5 ± 12.2 years, p=0.036), had longer sick leave (mean 128.5 ± 140.6) vs 67.6 ± 107.6 days/year, p=0.004), less often self-reported physical activity (35.1% ± 48.1 vs 53.4% ± 50.2, p=0.031), and reported lower pain levels (mean 6.1 ± 2.0 vs 7.1 ± 1.9 on a 0-10 numeric scale, p=0.002) .There was no significant difference regarding functional disability, pain duration, kinesiophobia, psychological status. In multivariate analysis, lower pain (odds ratio, OR: 0.95, 95% CI [0.91;0.99] for an increase of 1 point), absence of physical activity (OR: 0.84, 95% CI [0.72;0.98]) and longer sick leave (OR: 1.03, 95 % CI [1.01;1.05] for 30 more days of sick leave) were independently associated with orientation towards a FRP. Conclusion:Orientation towards FRPs was linked to pain, self-reported physical activity and sick leave. This confirms the biopsychosocial approach of FRPs for cLBP.

Objectives To assess the relationship between consumption of largely consumed beverages (coffee, tea, alcohol, and soft drinks) and the risk of RA. Methods The E3N Study (Étude Épidémiologique auprès des femmes de la Mutuelle Générale de l’Éducation Nationale) is a French prospective cohort including 98 995 women since 1990. Food and beverage consumption was assessed using a validated food-frequency questionnaire. Hazard ratios (HR) and their 95% confidence intervals (CI) for incident RA were estimated by Cox proportional hazards model. Results Among 62 631 women, 481 incident RA cases were identified. Consumptions of tea, alcohol, and sugar-sweetened soft drinks were not associated with RA risk. We observed a linear association between coffee consumption and RA risk (≥4 cups/day vs ≤1cup/day, HR = 1.24; 95% CI [0.94; 1.64], ptrend = 0.04), and a higher risk of RA with artificially-sweetened soft-drinks consumption (consumers vs not, HR = 1.66; 95% CI [1.12; 2.45]), particularly in never-smokers. Among ever-smokers, moderate liquor intake was associated with a reduced risk of RA (1–3 glasses/week vs non-consumers, HR = 0.63; 95% CI [0.43; 0.91]) and moderate wine consumption with a reduced risk of seropositive RA. Conclusion In a large cohort of women, tea, alcohol, and sugar-sweetened soft drinks consumption was not associated with RA risk, whereas consumptions of coffee (especially caffeinated coffee), and artificially-sweetened soft drinks were associated with higher RA risk, particularly among never-smokers. If further confirmed, these results could lead to novel mechanistic hypotheses and to simple prevention measures.