Keywords: Amino acids / Amines / Transamination / Rearrangement / Chiral resolution Biomimetic studies of pyridoxal and pyridoxamine models are of both fundamental and practical interest. This review examines (i) deracemization of α-amino acids with a chiral pyridoxal model, (ii) sensing of chirality of small molecules including α-, β-, and γ-amino acids, peptides, amino alcohols and diamines with an achiral pyridoxal model and (iii) stereospecific synthesis of chiral diamines with a chiral pyridoxamine model. A binol-based aldehyde is useful as a chiral pyridoxal model to deracemize a variety of α-amino acids to make D-amino acids. 2,2Ј-Dihydroxybenzophenone is useful
Review: use of a chiral pyridoxal model to make unnatural α‐amino acids with excellent stereoselectivity, chiral diamines from a chiral pyridoxamine model, computational studies; ca. 130 refs.
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