Purpose: To determine whether peritumoral hypointensity seen on hepatobiliary phase images of preoperative gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) is useful for predicting microvascular invasion of hepatocellular carcinoma (HCC). Materials and Methods:This study was approved by the Institutional Review Board. In all, 104 HCC masses in 104 patients who had undergone EOB-MRI and liver surgery within 1 month after EOB-MRI were evaluated. Two radiologists independently recorded the presence of a peritumoral hypointensity on hepatobiliary phase. Interobserver agreement was assessed and consensus records were used. Tumor size was measured. A chi-square test and independent t-test were used for univariate analysis. Multiple logistic regression was performed to determine factors for predicting microvascular invasion. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of peritumoral hypointensity were calculated.Results: Sixty HCCs had microvascular invasion and 44 did not. Interobserver agreement in determining peritumoral hypointensity was excellent (k ¼ 0.83). By univariate analysis, peritumoral hypointensity and tumor size were significant for predicting microvascular invasion of HCC. On multiple logistic regression analysis, only peritumoral hypointensity was significant in predicting microvascular invasion of HCC (P ¼ 0.013). The sensitivity, specificity, PPV, and NPV of peritumoral hypointensity were 38.3%, 93.2%, 88.5%, and 52.6%, respectively. Conclusion:Peritumoral hypointensity on the hepatobiliary phase of EOB-MRI is not sensitive but has high specificity for predicting microvascular invasion of HCC.

No abstract

Primary adenocarcinoma of the seminal vesicles is a rare neoplasm. Congenital seminal vesicle cysts are commonly associated with unilateral renal agenesis or dysgenesis. To the best of our knowledge, mucinous adenocarcinoma of the seminal vesicle cyst that's associated with an ectopic ureter opening into the seminal vesicle and ipsilateral renal agenesis has not been described in the radiological literature. We report here on the radiological findings of a primary adenocarcinoma of a seminal vesicle cyst in this condition.rimary tumors of the seminal vesicles are rare. Primary adenocarcinoma of the seminal vesicles commonly occurs in patients who over the age of 50. Congenital anomalies of the mesonephric duct are rare in males. Congenital seminal vesicle cysts are commonly associated with ipsilateral renal agenesis or dysgenesis (1). We present here the imaging findings of a primary adenocarcinoma of a seminal vesicle cyst associated with an ectopic ureter opening into a seminal vesicle and ipsilateral renal agenesis. CASE REPORTA 41-year-old man presented with terminal gross hematuria that was noted one month earlier. His past medical history was unremarkable except that he had suffered with prostatitis. The serum markers for prostate cancer, prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP) were normal. Carcinoembryonic antigen (CEA) was also in the normal range. Transrectal ultrasonography showed a well-demarcated, pear-shaped cystic lesion that included an echogenic papillary solid mass in his left seminal vesicle (Fig. 1A). Contrast-enhanced pelvic CT showed that the papillary solid mass originated from the wall of the left seminal vesicle cyst and it was mildly enhanced (Fig. 1B). A dilated ectopic ureter opening into the dilated left seminal vesicle was also seen. There was no evidence of any other pelvic tumors. Contrast enhanced abdominal CT at the level of the L4 vertebra demonstrated a small abnormal soft tissue density in the aorta's left lateral aspect, suggesting a dysgenetic or atrophic kidney (Fig. 1C). The axial T1-weighted (TR/TE: 540/12 ms) MR image showed high signal-intensity fluid in the seminal vesicle cyst (Fig. 1D). The coronal T2-weighted (TR/TE: 5500/136 ms) MR image demonstrated an approximately 7.8 6 5.2 cm papillary mass in the left seminal vesicle cyst (Fig. 1E). The sagittal T2-weighted image showed a markedly dilated ectopic ureter draining into the cyst (Fig. 1E). The cystoscopic findings showed bulging of the left hemitrigone on the left side of the bladder. The left ureteral orifice was absent.Radical excision of the left agenetic kidney, left ureter and seminal vesicle cyst and a

http://radiology.rsnajnls.org/cgi/content/full/249/3/810/DC1.

Primary spinal malignant melanoma is an extremely rare condition. We here describe a case of a 71-year-old Asian female presenting with left upper extremity tingling sensation. Computed tomography (CT) showed a homogeneously enhanced mass occupying the left neural foramen at the C6-7 level. Magnetic resonance imaging revealed enhanced mass in intra-and extradural space compressing the spinal cord at this level. It also widened the neural foramen mimicking neurofibroma or schwannoma. Partial resection of the mass was performed. Pathologic diagnosis of the mass was malignant melanoma. Postoperative whole body positron emission tomography/ CT scan demonstrated an intense 18 F-FDG uptake at the residual mass site without abnormal uptake at other sites in the body.