Anthocyanins, which are bioactive phytochemicals, are widely distributed in plants and especially enriched in tart cherries. Based on previous observations that tart cherry anthocyanins and their respective aglycone, cyanidin, can inhibit cyclooxygenase enzymes, we conducted experiments to test the potential of anthocyanins to inhibit intestinal tumor development in Apc(Min) mice and growth of human colon cancer cell lines. Mice consuming the cherry diet, anthocyanins, or cyanidin had significantly fewer and smaller cecal adenomas than mice consuming the control diet or sulindac. Colonic tumor numbers and volume were not significantly influenced by treatment. Anthocyanins and cyanidin also reduced cell growth of human colon cancer cell lines HT 29 and HCT 116. The IC(50) of anthocyanins and cyanidin was 780 and 63 microM for HT 29 cells, respectively and 285 and 85 microM for HCT 116 cells, respectively. These results suggest that tart cherry anthocyanins and cyanidin may reduce the risk of colon cancer.
Abstract:In the new era of IoT (Internet of Things), numerous gadgets and services include innovative IoT technologies that provide customers with convenience and improve their quality of life. Smart TVs are typical IoT devices that offer broadcasting services. However, they are susceptible to security intrusions via e-mail, media players, cameras, and internet connectivity. The frequency of hacking through malicious applications installed in Smart TV has rapidly increased. Therefore, appropriate countermeasures should be developed immediately. In April 2017, we (with LG electronics) received the 'world-first' Common Criteria EAL2 (Evaluation Assurance Level 2) certification for Smart TVs. As far as we know, no Smart TV has received a Common Criteria EAL2 security certification until now. This article describes our experience with the certification process and examines several security and reliability aspects of Smart TVs.
IoT is gaining importance in our lives and in the military too. With the application of IoT paradigm in the military and the weapon system's connectivity to the network, this facilitates the commanders to make real-time decisions. However, cybersecurity threats to weapon systems intensify along with the growing of IoT's benefits. Coping with these cybersecurity threats nowadays, we require the implementation of "security by design" concept during weapon system development throughout the system lifecycle, but not traditional security solutions. Since only developed countries are capable of developing systems on their own, they adopt "security by design" when developing new weapon systems; another approach to acquire weapon systems is through import if a country cannot develop the whole weapon system. However, few studies have been done on the security evaluation framework that could be used upon purchase and integration of the developed weapon system. In this paper, we proposed a novel security evaluation framework that could be used to integrate IoT devices and components into the weapon system and a method to address cybersecurity requirements using international standard security control.
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