Purpose Retinal microsurgery requires extremely delicate manipulation of retinal tissue where tool-to-tissue interaction forces are usually below the threshold of human perception. Creating a force-sensing surgical instrument that measures the forces directly at the tool tip poses great challenges due to the interactions between the tool shaft and the sclerotomy opening. Methods We present the design and analysis of a force measurement device that senses distal forces interior to the sclera using 1-cm long, 160 µm diameter Fiber Bragg Grating (FBG) strain sensors embedded in a 0.5 mm diameter tool shaft. Additionally, we provide an algorithm developed to cancel the influence of environmental temperature fluctuations. Results The force-sensing prototype measures forces with a resolution of 0.25 mN in 2 DOF while being insensitive to temperature. Conclusion Sub-millinewton resolution force sensors integrated into microsurgical instruments are feasible and

The electrical resistivity of a thermoresponsive polyurethane shape-memory polymer ͑SMP͒ filled with micron sized Ni powders is investigated in this letter. We show that, by forming conductive Ni chains under a weak static magnetic field ͑0.03 T͒, the electrical conductivity of the SMP composite in the chain direction can be improved significantly, which makes it more suitable for Joule heat induced shape recovery. In addition, Ni chains reinforce the SMP significantly but their influence on the glass transition temperature is about the same as that of the randomly distributed Ni powders.

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MRI and MRSI have the potential to identify cancer foci and direct TRUS in patients with a previous negative TRUS biopsy. Further, larger studies are required to quantify the amount of benefit.

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The authors are developing devices for semi-autonomous or autonomous locomotion in the gastrointestinal (GI) tract. In this paper, they illustrate the systematic approach to the problem of "effective" locomotion in the GI tract and the critical analysis of "inchworm" locomotion devices, based on extensor and clamper mechanisms. The fundamentals of locomotion and the practical problems encountered during the development and the testing (in vitro and in vivo) of these devices are discussed. A mini device capable of propelling itself in the colon and suitable to perform, at least, rectum-sigmoidoscopy (the tract where approximately 60% of all colon cancers are found) is presented. This paper introduces preliminary, but useful, concepts for understanding, modeling and improving the performance of virtually any existing and novel devices for endoscopy of the GI tract.

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Electronic medical devices have become an indispensable part of modern healthcare. Currently, a wide variety of electronic medical devices are being used to monitor physiological parameters of the body, perform therapy and supplement or even entirely replace complex biological functions. Cardiac pacemakers, cardioverter-defibrillators and cochlear implants are a few examples of such medical devices. Proper functionality of these devices relies heavily on the continuous supply of a sufficient amount of electricity to them. In this sense, a reliable, safe and convenient method for the provision of energy is very crucial. Various approaches have been developed to fulfil the divergent and challenging energy requirements of medical devices. In this article, we present a brief overview of the energy requirements of medical devices and review the existing and emerging energy sources for application in these devices, particularly wearable and implantable devices.