Serum lipids (triglyceride, cholesterol, HDL cholesterol, LDL cholesterol, and VLDL) were measured in clinically healthy broilers, ostriches, cattle, and sheep (15 females and 15 males of each species).The results were as follows: the mean±SD of triglyceride, cholesterol, HDL-C, LDL-C, and VLDL in broiler serum was 190±82, 183±46, 118±24, 24±8, and 38±16 mg/dl; in ostrich serum 301± 90, 205±78, 57±25, and 87±16 mg/dl; in cattle serum 39± 1 2, 92±20, 67±16, 16±7, and 8±2 mg/dl; and in sheep serum 32±14, 97±27, 49±16, 42±14, and 6±3 mg/dl, respectively. The serum lipid values showed highly significant difference between broilers and ostriches compared with cattle and sheep (P<0.05). There were no significant differences between the two sexes (P>0.05). Considering the nutritional analysis of the meat from each species, according to results, there seems to be an inverse correlation between these factors in serum and meat.