Objective We analyzed the expression of anger according to the perceived quality of sleep in university students. Methods A total sample of 1252 students participated in the study, with an average age of 23.58 years. Using an ex-post facto design and an incidental sampling procedure, the Pittsburgh Sleep Quality Index and the State-Trait Anger Expression Inventory-2 were applied. Results Students with poor sleep quality (PSQI scores> 5) scored higher on the subscales of STAXI-2, showing higher risk of obtaining superior values in Trait Anxiety [OR=1.90] and in the Index of Expression of Anger [OR=1.56], but not in Internal Control of Anger. Conclusions There appears to be a marked relationship between quality of sleep and anger, and it is suggested that sleep hygiene programs can help to reduce the negative consequences of poor sleep quality in terms of health and academic performance in students.