Iniencephaly is a rare malformation characterized by the triad of occipital bone defect, cervical dysraphism and fixed retroflexion of the fetal head. Because of its almost invariable lethal prognosis, termination of pregnancy is commonplace when this condition is diagnosed before viability. In this report we describe eight cases of iniencephaly prenatally diagnosed by ultrasound between 18 and 28 weeks of gestation and discuss the subsequent obstetric management in a country where elective abortion is illegal. Prenatal karyotyping was performed in seven cases, revealing a normal complement in all fetuses. One pregnancy miscarried at 24 weeks. Uneventful vaginal delivery was accomplished in six of the remaining seven cases, one delivered spontaneously at 29 weeks and five were induced between 28-32 weeks due to increasing polyhydramnios. In the remaining case the pregnancy progressed to 35 weeks, at which time spontaneous labour began and an emergency Caesarean section was performed because of malpresentation. There were no survivors in this series. We conclude that, in countries were elective abortion is not allowed, women carrying an iniencephalic fetus may benefit from preterm induction of labour in order to avoid labour dystocia, maternal trauma during delivery and the risks of a Caesarean section.
Iniencephaly is a rare malformation characterized by the triad of occipital bone defect, cervical dysraphism and fixed retroflexion of the fetal head. Because of its almost invariable lethal prognosis, termination of pregnancy is commonplace when this condition is diagnosed before viability. In this report we describe eight cases of iniencephaly prenatally diagnosed by ultrasound between 18 and 28 weeks of gestation and discuss the subsequent obstetric management in a country where elective abortion is illegal. Prenatal karyotyping was performed in seven cases, revealing a normal complement in all fetuses. One pregnancy miscarried at 24 weeks. Uneventful vaginal delivery was accomplished in six of the remaining seven cases, one delivered spontaneously at 29 weeks and five were induced between 28-32 weeks due to increasing polyhydramnios. In the remaining case the pregnancy progressed to 35 weeks, at which time spontaneous labour began and an emergency Caesarean section was performed because of malpresentation. There were no survivors in this series. We conclude that, in countries were elective abortion is not allowed, women carrying an iniencephalic fetus may benefit from preterm induction of labour in order to avoid labour dystocia, maternal trauma during delivery and the risks of a Caesarean section.
Poster abstracts triple test had 100% sensitivity and 92% specificity. For other fetal abnormalities, sensitivity and specificity of first trimester screening were 28.5% and 96.6% respectively. Sensitivity and specificity of the triple test were 88% and 94.8% for detecting these other fetal abnormalities. Conclusions:The increased sensitivity of the triple test for picking up the other fetal abnormalities was thought to be the result of AFP measurement. It seems wise to screen for Down's syndrome with the first trimester screening programme and then screen for other fetal abnormalities during the second trimester by measuring maternal serum AFP level only. Objective: Fetal ductus venosus flow at 13-14 weeks' gestation is on of the best tests to identify fetuses with cardiac abnormality. Enlarged fetal nuchal translucency/NT/ is a well established ultrasonographic marker for aneuploidy screening. Our aim is to assess the incidence of reverse flow during atrial contraction at ductus venosus in fetuses with normal NT and correlation with cardial abnormalities. Material and methods: At 13-14 weeks' gestation were obtained ductus venosus Doppler flow velocity, during measurement of NT in 344 fetuses. Results: The incidence of reverse flow was 13.5% of fetuses with increased NT/3 mm/ and 4.8% with normal NT. Among the fetuses NT was increased in/13/ 4.1%. There was no cardiac malformation observed in fetuses with normal NT, and cardial abnormality was found with increased NT. Conclusion: Our results suggest that the reversed flow in fetuses with normal NT is not associated with cardial malformations. P025 P026Association of increased nuchal translucency and ductus venosous assessment between 11 to 14 weeks of gestation
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.