Objectives: (1) To determine frequency of urinary tract infection among pyuric diabetic patients. (2) To determine sterile pyuria frequency among pyuric diabetic patients. (3) To determine factors predisposing to urinary tract infection. Methods: This is a non randomized, prospective observational study done in tertiary care set up of Dow University of Health Sciences, Karachi. Data collection done from June 2013 till August 2013. Sampling was done by convenient method, sample size of 97. Inclusion criteria was all adult (above 16) patients with diabetes mellitus and pyuria (more than 4 pus cells /HPF) whose urine culture report was also available. Verbal consent was sought from patients. All data was collected on a Performa. Data was maintained and analyzed on SPSS version 16. Results: Total number of pyuric diabetic patients in study was 97. Frequency of Urinary tract infection was 59/97 (60.82%), prevalence of culture negative sterile pyuria was found 38/97 (39.17%). Urinary tract infection was found to be more in females with lower urinary tract symptoms and flank pains. Stone disease, obstructed pelvicalyceal system, proteinuria, high serum creatinine and positive nitrites were found more in culture positive patients than in culture negative pyuric patients. Conclusions: Pyuric diabetic patients in our study population were found to have culture positive UTI in 60.82% and culture negative sterile pyuria among 39.17% of patients. UTI was found more in females, in symptomatic patient and with abnormal urinary tract anatomy and function.
Introduction: The hepatitis C virus (HCV) is a Flaviviridae-related virus that causes a systemic illness that can be transmitted. HCV is a blood-borne infection that primarily affects the liver. HCV diagnosis that is accurate and timely is critical in significantly reducing the risk of morbidity and mortality. The goal of this study was to find out the Hepatitis C in chronic renal failure patients who are on hemodialysis. Method: This descriptive cross-sectional study was carried out in the Dialysis Unit of the Khyber Teaching Hospital (KTH) Peshawar's Department of Nephrology. From September to December 2017, this study took place over four months. The study included a total of 114 patients, regardless of their age or gender. Hepatitis C was detected in whole blood samples collected from 114 healthy people using an immunochromatography method. The data was analyzed using SPSS v.22. Result: The Immunochromatography technique for HCV was used to analyze 114 blood samples from recruited individuals. Male patients were 52.6% of the total, while female patients made up 47.4%. The study found that 24.56% of male patients were positive, while 28.07% of female patients were positive. Overall, the technique's sensitivity and specificity were 83.1% and 72.7%, respectively. Conclusion: It is concluded that the HCV rapid testing is still sensitive and specific for detecting hepatitis C virus, it should be used in routine clinical settings for early hepatitis C virus diagnosis when advanced diagnostic options are restricted. Keywords: HCV, Hepatitis C virus, Nephrology, Dialysis
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