IntroductionChronic fatigue syndrome (CFS) is a widely recognized problem, characterized by prolonged, debilitating fatigue and a characteristic group of accompanying symptoms, that occurs four times more frequently in women than in men. The aim of the study was to determine the existence of oxidative stress and its possible consequences in female patients with CFS.Material and methodsTwenty-four women aged 15-45 who fulfilled the diagnostic criteria for CFS with no comorbidities were recruited and were age matched to a control group of 19 healthy women. After conducting the routine laboratory tests, levels of the lipid oxidation product malondialdehyde (MDA) and protein oxidation protein carbonyl (CO) were determined.ResultsThe CFS group had higher levels of triglycerides (p = 0.03), MDA (p = 0.03) and CO (p = 0.002) and lower levels of HDL cholesterol (p = 0.001) than the control group. There were no significant differences in the levels of total protein, total cholesterol or LDL cholesterol.ConclusionsThe CFS group had an unfavorable lipid profile and signs of oxidative stress induced damage to lipids and proteins. These results might be indicative of early proatherogenic processes in this group of patients who are otherwise at low risk for atherosclerosis. Antioxidant treatment and life style changes are indicated for women with CFS, as well as closer observation in order to assess the degree of atherosclerosis.
Changes in the structure of consumers' (tourists') needs that shape tourism in accordance with the modern way of life attribute greater importance to different types of consumers/tourists. Understanding consumer behaviour (tourists as consumers) is significant in terms of tourism destination management. This paper presents the results of a research conducted with the aim of identifying activities (visiting cultural and historical attractions, sport and recreation, health, fun, gastronomy, shopping, cultural entertainment events) that consumers/tourists prefer in a tourist destination depending on their age and family structure. Two hypotheses were set in this paper: H 1 : There is a statistically significant difference between the age of tourists and the activity preferences in a tourist destination; and H 2 : There is a statistically significant difference between the family structure of tourists and the activity preferences in a tourist destination. The sample included 1117 respondents from the area of the Autonomous Province of Vojvodina. A survey was conducted from January to March 2017. In accordance with the defined hypotheses, descriptive statistics and a statistical test of multivariate analysis of variance (MANOVA) were used.
Sustainable tourism should maintain a high level of tourist satisfaction, so identifying components of tourism destination image plays an important role in destination management and marketing. This study aims to explore issues related to the image of a rural tourism destination, with the focus on the cognitive component. It also aims to analyze three dimensions of the cognitive component: functional, mixed, and psychological. Furthermore, this study gives the answer to the question of which dimension of the cognitive component makes the most significant impact on the general image of a rural tourism destination. The sample comprised 562 respondents. Data analysis included exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and structural equation modeling (SEM). The results indicate the existence of three dimensions of the cognitive component, and it can be concluded that the psychological dimension of the cognitive component has the most significant impact on the general image of a rural tourism destination.
BackgroundChronic fatigue syndrome (CFS) is characterized by medically unexplained persistent or reoccurring fatigue lasting at least 6 months. CFS has a multifactorial pathogenesis in which oxidative stress (OS) plays a prominent role. Treatment is with a vitamin and mineral supplement, but this therapeutic option so far has not been properly researched.Material/MethodsThis prospective study included 38 women of reproductive age consecutively diagnosed by CDC definition of CFS and treated with a multivitamin mineral supplement. Before and after the 2-month supplementation, SOD activity was determined and patients self-assessed their improvement in 2 questionnaires: the Fibro Fatigue Scale (FFS) and the Quality of Life Scale (SF36).ResultsThere was a significant improvement in SOD activity levels; and significant decreases in fatigue (p=0.0009), sleep disorders (p=0.008), autonomic nervous system symptoms (p=0.018), frequency and intensity of headaches (p=0.0001), and subjective feeling of infection (p=0.0002). No positive effect on quality of life was found.ConclusionsTreatment with a vitamin and mineral supplement could be a safe and easy way to improve symptoms and quality of life in patients with CFS.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.