It is concluded that the novel peptide KV11 is an effective inhibitor of retinal pathologic angiogenesis with a sufficient retinal penetration and a favorable safety profile and may provide a promising alternative for ocular antiangiogenic therapy.
In some applications of linear ultrasonic motors (LUSMs), not installing speed/position sensors can reduce the size and cost of the system, changes in load will cause fluctuations in the speed of the LUSM. To eliminate the influence of load changes on speed, a speed sensorless control scheme based on stator vibration amplitude compensation (SSCBVC) is proposed. This scheme is implemented under the framework of the stator vibration amplitude-based speed control (VBSC) and frequency tracking. Based on the stator vibration amplitude-speed and the output force-speed curves of the LUSM, the relationship between the load changes and stator vibration amplitude (SVA) to be compensated is established, realizing a speed sensorless control of the LUSM under variable load conditions. The experimental results show that the maximum fluctuation of the speed is about 2.2% when the output force changes from 0 to 6 N with SSCBVC. This scheme can effectively reduce the influence of load changes on the speed of the LUSM without using speed/position sensors.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.