Objectives To evaluate the feasibility of using ultrasoundobtained tumor depth (TD) and margin shape (MS) to predict the prognosis of tongue cancer. Methods Fifty-two Japanese patients with tongue cancer who underwent ultrasound examination between 2007 and 2012 were retrospectively evaluated. TD was measured at the deepest portion of the tumor. MS was classified as ''pressure,'' ''wedge-shaped,'' or ''permeated.'' Prognosis was assessed by local recurrence, lymph node metastasis, and overall survival rate. We classified the patients into a good prognosis group and poor prognosis group. Relationships among TD, MS, and patient prognosis were evaluated using Spearman rank correlation. A regression formula to predict prognosis using TD and MS was derived.Results The correlation between TD and MS was significant (Spearman rank correlation q = 0.552, p \ 0.01).Using a structure matrix, we identified the contribution of both predictors from an ultrasound image. The contribution of TD was 0.796, while that of MS was better at 0.906. The prognosis could be predicted using the following regression formula: D ¼ À2:801 þ 0:093x þ 0:872y, where D prognosis (risk probability), x = TD (mm), and y = MS (grade). The average value for good risk probability was -0.254 (standard deviation, 0.962), while that for poor risk probability was 0.566 (standard deviation, 1.08) (p \ 0.05). The cut-off value for classifying cases was -0.00169. Using the formula above, 73.1 % of patients in the poor prognosis group were correctly classified.Conclusions MS and TD are useful predictors of tongue cancer prognosis.
Pendahuluan: Pada era globalisasi masyarakat indonesia mulai sadar akan kesehatan gigi dan mulut, kesadaran masyarakat tersebut tidak hanya mengenai penyakit gigi dan mulut, melainkan juga masalah estetik gigi, estetik yang baik dapat dilakukan dengan banyak cara salah satunya tindakan penumpatan, bahan tumpatan yang biasa digunakan yaitu resin komposit. Umumnya dokter gigi memilih resin komposit sebagai bahan tambal karena sifat estetik yang sewarna dengan gigi sehingga memberikan hasil yang memuaskan. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh sari buah pir terhadap perubahan warna resin komposit. Bahan dan Metode: Sampel penelitian ini adalah komposit nanohibrid dengan ketebalan 4 mm dan diameter 5 mm. Penelitian ini menggunakan metode Eksperimental Laboratorium yaitu pengujian yang dilakukan di laboratorium dengan bentuk penelitian berupa Pre-post Test Control Design. Jenis penelitian yang dilakukan adalah True Eksperimental Laboratorium. Uji statistic menggukanakan Wilcoxon. Hasil: Hasil penelitian ini menunjukkan terdapat perubahan warna pada resin komposit setelah direndam dalam jus buah pir dimana nilai rata-rata setelah direndam dalam jus buah pir pada kelompok kopi yaitu 12,00 pada kelompok teh 12,778 dan pada kelompok fanta 7,667 dan berdasarkan uji statistic memperoleh nilai signifikan P<0.00. Kesimpulan: Hipotesis alternatif penelitian ini diterima, dan hasil penelitian ini menunjukkan adanya perubahan warna pada resin komposit setelah direndam dalam sari buah pir.
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