SUMMARYBackground: Diverticular disease emerged as a common problem in Western countries over the course of the 20th century. Aims: To determine the time trends in diverticular disease for hospital admissions in England between

Summary Background

One in 4 and 1 in 9 children with nephrotic syndrome in the present study had PSCC and raised IOP respectively. Cumulative dose and duration of steroid therapy were not significantly associated with PSCC or raised IOP. The present study emphasizes the need for regular ocular evaluation and also to explore additional factors in causation of steroid induced ocular complications.

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Background: Glanzmann thrombasthenia (GT) is a globally rare inherited disorder of hemostasis. Objectives: To describe the clinical profile of GT in a tertiary care center in Southern India. Methods: A retrospective chart review of all children with GT was performed between January 2005 and August 2017 in the Department of Paediatrics. Results: A total of 48 patients (representing 43 families) were included. Median age at diagnosis was 2.75 years (interquartile range: 1.5 to 6.75). Two thirds had an onset of bleeding within the first 2 years of life. Sixty-seven percent were born out of consanguineous marriage. The common symptoms were epistaxis, gingival bleeding, and ecchymoses. Neonatal onset of bleeding manifested as purpura, epistaxis, and intracranial hemorrhage. Postsurgical bleeding and menorrhagia were unique presentations in adolescence. About 25% had life-threatening hemorrhage while 50% had growth retardation due to chronic anemia. Conclusions: GT is relatively more common in areas of Southern India due to the higher prevalence of consanguinity. Chronic anemia can contribute to growth stunting in these patients.