Acquired factor X (FX) deficiency is a rare but serious complication of primary amyloidosis, presumably caused by the binding of amyloid proteins to the clotting factors. The prolonged prothrombin time, partial thromboplastin time, and low FX level, which are correctable by mixing study, are the disease hallmarks. An immediate goal of care is to stop bleeding. Clotting factor replacement requires close monitoring of coagulogram and FX levels due to varying FX clearance among patients. High-purity FX is currently approved for hereditary FX deficiency and has been successfully used in some acquired FX deficiency cases. Ongoing bleeding risk complicates the treatment decision. Novel therapies yielding rapid and deep response reduce amyloid protein production and improve long-term outcome.
Diabetes self-management education and support (DSMES) is a significant component of diabetes care. However, our previous study indicated a lack of patient-centered DSMES during clinic visits. Therefore, we developed a patient-centered DSMES education aid named SEE-Diabetes (Support-Engage-Empower-Diabetes) to facilitate providers and patients in making shared decisions (Figure 1). We aimed to validate the content of SEE-Diabetes by interviewing 11 diabetes patients aged 65 and older, and 8 providers. Participants were asked to evaluate SEE-Diabetes statements incorporated in the Patient Education section by answering focused questions. The participants were asked if the statements were easy to read, helpful, and if they provided additional value to address the concerns, needs, and preferences of older people with diabetes. They were also asked if they would use SEE-Diabetes to improve their diabetes care. Thematic analysis revealed most participants agreed that it was easy to read and understand. Most of them found it very helpful, added value to the clinic note, and would use it to help take care of their diabetes. However, one patient shared it was unnecessary for long-term diabetes patients. Some providers shared concerns about lack of time. Future studies will evaluate the usability and feasibility of SEE-Diabetes as an educational tool in clinical practice.
Disclosure
S.Dejhansathit: None. P.Narindrarangkura: None. M.A.Day: None. S.A.Boren: None. U.Z.Khan: None. E.J.Simoes: None. M.Kim: None.
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