BackgroundSelf‐collection of nasal swabs could improve the timeliness of influenza virus detection in older adults.ObjectivesMeasure the acceptability, adequacy, timeliness, and validity of self‐collected nasal swabs among adults >65 years in Thailand.MethodsOur evaluation consisted of two parts: a one‐month study among randomly selected, community‐dwelling older adults to simulate community‐based surveillance for acute respiratory infections (ARI); and a clinic study of older adults with ARI to evaluate the sensitivity and specificity of self‐collected nasal swabs for influenza virus infection compared with healthcare worker (HCW)‐collected nasal and nasopharyngeal swabs.ResultsIn the community study, 24% of participants experienced an ARI during the observation period. All (100%) participants with an ARI self‐collected nasal swabs within 72 hours of symptom onset of which 92% were considered adequate samples. In the clinic study, 45% of patients with ARI presented within 72 hours of symptom onset. The sensitivity of self‐collected nasal swabs for detection of influenza virus infection was 78% (95% CI 40‐97) compared to nasopharyngeal and 88% (95% CI 47‐100) compared to nasal swabs collected by HCWs. Specificity was 100% (95% CI 97‐100) compared to both methods. Self‐collection of nasal swabs was found acceptable by 99% of participants in both studies.ConclusionsSelf‐collection of nasal swabs was acceptable to older adults in Thailand who were able to take adequate samples. Self‐collection of nasal swabs may improve the timeliness of sample collection but lower sensitivity will need to be considered.

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Background: Opisthorchis viverrini is one of the endemic helminths in Thailand. Nonetheless, O. viverrini still exist and raise concerns regarding public health. This study aimed to evaluate the current prevalence of O. viverrini infections and underlying risk factors among rural communities in Northeast Thailand. Methods: A cross-sectional study was conducted between Sep and Dec 2019 in Phon Sawan district in Nakhon Phanom Province, Thailand. The participants were selected using a voluntary sampling method after the proportional allocation of the total sample size. Demographic data were collected using a standardized questionnaire. One stool sample was collected from each participant and the presence of O. viverrini and other intestinal parasite infections were determined using the modified Kato-Katz technique. Results: Overall, 250 participants aged 21 yr or older were enrolled. Overall, the prevalence of O. viverrini and Strongyloides stercoralis was 24% (95% confidence interval [CI]: 18.8-29.8) and 1.2% (95% CI: 0.2-3.5), respectively. Of the positive O. viverrini cases, the parasite rate significantly differed between gender, age group and in those who had a history of eating raw fish and taking the anti-helminthic drug (all P<0.05). Nevertheless, multivariate regression analysis among O. viverrini cases revealed that only being male (adjusted odds ratio [aOR] 1.9 [95% CI: 1.1 – 3.6], P = 0.033) and aged ≥61 yr (aOR 6.7 [95% CI: 1.4 – 32.5], P=0.018) were positively associated with a higher risk of O. viverrini infection. Conclusion: Opisthorchiasis and strongyloidiasis are still endemic in this area and there is a need for projects to eliminate these parasites.