Background: Thyroid hormones play a role in growth and development of neuromuscular system. Hypothyroidism causes neurological dysfunctions like peripheral & entrapment neuropathy, cerebellar ataxia, myxedema coma etc 1 . Studies show that motor symptoms increases with increase TSH levels. Nerve conduction study when conducted early in the course of disease helps in medical management of neuropathies before starting surgical treatment. This study assessed median motor parameters in recently diagnosed and untreated hypothyroid patients. Objectives: To study the correlation between TSH values and median motor nerve parameters in newly diagnosed hypothyroid patients Material & Methods: 270 hypothyroid males and females with age 20 to 50 years were included. Patients with neurological disorders, diabetes mellitus, those taking drugs causing neuropathy, alcoholics and smokers were excluded. Study design was descriptive All patients underwent electrophysiological studies in the department of Neuromedicine, GTDMC, Alappuzha for one year. Study variables were distal latency, conduction velocity and amplitude of median motor nerve, TSH, fT3 & fT4. Median motor nerve parameters were correlated with TSH values and the results analysed statistically by SPSS software. Results: Datas were analysed with SPSS version 18 using student t test and chi square test and p value <0.05 was considered as significant. Observations were represented both graphically and numerically. Conclusion: In this study, strong association was found between TSH values and altered motor nerve parameters especially in distal latency. It may be due to entrapment neuropathy where deposition of mucinous substances around the peripheral nerves occurs. Early diagnosis and treatment can prevent the impairment of motor conduction parameters.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.