Table of contentsP001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP effluxR. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. EllisP002 - Lower serum immunoglobulin G2 level does not predispose to severe flu.J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez GallegoP003 - Brain protective effects of intravenous immunoglobulin through inhibition of complement activation and apoptosis in a rat model of sepsisF. Esen, G. Orhun, P. Ergin Ozcan, E. Senturk, C. Ugur Yilmaz, N. Orhan, N. Arican, M. Kaya, M. Kucukerden, M. Giris, U. Akcan, S. Bilgic Gazioglu, E. TuzunP004 - Adenosine a1 receptor dysfunction is associated with leukopenia: A possible mechanism for sepsis-induced leukopeniaR. Riff, O. Naamani, A. DouvdevaniP005 - Analysis of neutrophil by hyper spectral imaging - A preliminary reportR. Takegawa, H. Yoshida, T. Hirose, N. Yamamoto, H. Hagiya, M. Ojima, Y. Akeda, O. Tasaki, K. Tomono, T. ShimazuP006 - Chemiluminescent intensity assessed by eaa predicts the incidence of postoperative infectious complications following gastrointestinal surgeryS. Ono, T. Kubo, S. Suda, T. Ueno, T. IkedaP007 - Serial change of c1 inhibitor in patients with sepsis – A prospective observational studyT. Hirose, H. Ogura, H. Takahashi, M. Ojima, J. Kang, Y. Nakamura, T. Kojima, T. ShimazuP008 - Comparison of bacteremia and sepsis on sepsis related biomarkersT. Ikeda, S. Suda, Y. Izutani, T. Ueno, S. OnoP009 - The changes of procalcitonin levels in critical patients with abdominal septic shock during blood purificationT. Taniguchi, M. OP010 - Validation of a new sensitive point of care device for rapid measurement of procalcitoninC. Dinter, J. Lotz, B. Eilers, C. Wissmann, R. LottP011 - Infection biomarkers in primary care patients with acute respiratory tract infections – Comparison of procalcitonin and C-reactive proteinM. M. Meili, P. S. SchuetzP012 - Do we need a lower procalcitonin cut off?H. Hawa, M. Sharshir, M. Aburageila, N. SalahuddinP013 - The predictive role of C-reactive protein and procalcitonin biomarkers in central nervous system infections with extensively drug resistant bacteriaV. Chantziara, S. Georgiou, A. Tsimogianni, P. Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, G. Micha, E. Chinou, G. MichaloudisP014 - Changes in endotoxin activity assay and procalcitonin levels after direct hemoperfusion with polymyxin-b immobilized fiberA. Kodaira, T. Ikeda, S. Ono, T. Ueno, S. Suda, Y. Izutani, H. ImaizumiP015 - Diagnostic usefullness of combination biomarkers on ICU admissionM. V. De la Torre-Prados, A. Garcia-De la Torre, A. Enguix-Armada, A. Puerto-Morlan, V. Perez-Valero, A. Garcia-AlcantaraP016 - Platelet function analysis utilising the PFA-100 does not predict infection, bacteraemia, sepsis or outcome in critically ill patientsN. Bolton, J. Dudziak, S. Bonney, A. Tridente, P. NeeP017 - Extracellular histone H3 levels are in...

Summary Background 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov , NCT03471494 . Findings Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding National Institute for Health Research Global Health Research Unit.

it is necessary to break with the dichotomy between theory and practice and promote the articulation of content with action, introducing the student as the author of their own knowledge.

RESUMO:A avaliação realizada pelos enfermeiros constitui um processo indispensável para o tratamento de feridas. Objetivos: averiguar os aspectos considerados pelos enfermeiros no processo de avaliação de feridas; identificar os recursos materiais utilizados para proceder à avaliação; investigar o seguimento de protocolos e possíveis dificuldades na sua realização. Estudo exploratório-descritivo, de natureza qualitativa, realizado junto a 14 enfermeiras de quatro hospitais públicos de João Pessoa -PB. Os dados foram coletados durante agosto e setembro de 2005, através de entrevistas gravadas e não-gravadas. Para análise das respostas aplicou-se a técnica do Discurso do Sujeito Coletivo. Verificouse que a falta de material conduz a uma avaliação superficial; que a ausência de protocolo dificulta a avaliação e, que a imposição médica e a falta de experiência e treinamento específicos foram às principais dificuldades reveladas. Evidenciou-se a necessidade de criar condições materiais e aprimorar os conhecimentos científicos em relação ao processo de avaliação de feridas. ABSTRACT:Nursing evaluation constitutes an indispensable process in treating wounds. The objectives of this article are to verify the aspects considered by nurses in the wound evaluation process, identify the material resources used in order to proceed to the evaluation, and to investigate adherence to protocols and possible difficulties in their execution. This is an exploratory-descriptive study of qualitative nature, carried out among 14 nurses from four public hospitals in João Pessoa, PB, Brazil. The data was collected during August and September of 2005 through recorded and non-recorded interviews. In order to analyze the responses given, the collective subject technique was applied. This study verified that a lack of material leads to a superficial evaluation; that the absence of protocol makes the evaluation difficult; and medical imposition, the lack of experience, and the lack of specific training were the main difficulties revealed. The needs to create material conditions and improve scientific knowledge regarding the wound evaluation process were evidenced. RESUMEN:La evaluación hecha por los enfermeros constituye un proceso indispensable para el tratamiento de heridas. Objetivos: Averiguar los aspectos considerados por los enfermeros en el proceso de evaluación de las heridas; identificar los recursos materiales utilizados para proceder a la evaluación; investigar el resultado de los registros y de las posibles dificultades en su realización. Es un estudio Exploratorio-descriptivo, de naturaleza cualitativa, realizado junto con 14 enfermeros de cuatro hospitales públicos de la ciudad de João Pessoa -PB. Los datos fueron recolectados durante el mes de agosto y septiembre de 2005, por medio de entrevistas grabadas y no grabadas. Para el análisis de las respuestas se empleó la técnica del Discurso del Sujeto Colectivo. Se verificó que la falta del material lleva a una evaluación superficial, que la falta de registros dificulta la evaluaci...