Introduction to epilepsy and related disorders 2.1. Incidence and prevalence 2.2. Causes of epilepsy 2.3. Types of seizure 2.4. Types of epilepsy 2.5. Related disorders 2.5.1. Severe myoclonic epilepsy of infancy 2.5.2. West syndrome 2.5.3. Lennox-Gastaut syndrome 2.5.4. Landau-Kleffner syndrome 2.5.5. Hemifacial spasm 2.5.6. Trigeminal neuralgia 2.6. Diagnosis 2.7. Medical management of epilepsy: general principles 2.8. Non-pharmacological treatment of epilepsy 2.8.1. Surgery 2.8.2. Vagus nerve stimulator 2.8.3. Ketogenic diet 3. The challenge of developing anti-epileptic drugs 3.1. Discovery and development of AEDs 3.2. Rational drug discovery in a perfect world 3.3. Etiology of epilepsy 3.3.1. Genes implicated in epilepsy 3.3.2. Therapeutic strategies suggested by these mechanisms 3.4. Animal models of epilepsy 3.5. Known reference compounds 3.6. Objective, reliable clinical outcomes 3.7. Other challenges in clinical development 3.8. Toxicity issues 3.9. Conclusion 4.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.