Key PointsQuestionAre angiotensin receptor blockers associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors?FindingsIn this case-control study of 964 older adults who died by suicide and 3856 matched control participants, compared with angiotensin-converting enzyme inhibitors, exposure to angiotensin receptor blockers was associated with a higher risk of suicide. Findings were consistent in a sensitivity analysis that excluded individuals with a history of self-harm.MeaningAngiotensin receptor blockers may be associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors.
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