Acne is a chronic inflammatory disease of pilosebaceous units. Although the acne isnot a life threatening disease, studies have revealed that it has significant effect on self-image and quality of life. The purpose of this paper was to investigate the health-related quality of life in patients with acne in an Iranian context. Dermatology Life Quality Index (DLQI) and Cardiff Acne Disability Index (CADI) were used for measuring quality of life, and severity of acne was measured by Global Acne Grading System (GAGS). The mean (±SD) of DLQI and CADI scores was 6.42 (±4.77) and 5.97 (±2.97), respectively. Acne influenced the quality of life in 51.8% of patients from moderate to very much, and the quality of life was affected by the severity of acne (P < 0.01). Since acne has significant effects on patient's quality of life, the management of patients with acne requires more attention to different aspects of quality of life.

Background -Hand eczema is among the most common dermatological diseases with a chronic course. It has undesirable psychological, social and occupational outcomes affecting patient's quality of life. Objective -The aim of the present study was to study the quality of life of patients with hand eczema in an Iranian population. Methods and Results -This cross-sectional study was performed on 196 patients with hand eczema through clinical exam and filling specific questionnaires. Hand Eczema Severity Index (HECSI) and Dermatology Life Quality Index (DLQI) were used for studying the disease severity and quality of life, respectively. Mean±SD of HECSI and DLQI scores were 57.05±48.85 and 14.80±5.79 respectively. In 94% of cases, hand eczema had significant effect on patients' quality of life. Based on DLQI, symptoms, feelings and personal relationships were the most affected aspects. There was a significant positive relationship between DLQI and HECSI scores (p<0.05). No significant difference was found in the quality of life based on age, sex and the disease duration. Conclusions -Since hand eczema significantly affects the quality of life, beside medical treatments, attention to psycho-social and occupational outcomes of the disease is highly recommended.