Bis(mexylamino)triazines have been identified as a family of compounds showing an exceptional propensity to form glassy phases as opposed to crystals. The particularities of this family of compounds are their ability to self-assemble through hydrogen bonding in well-defined patterns to form supramolecular aggregates which pack poorly and the wide range of glass transition temperatures (T(g)) that can be attained through minor structural modifications. Representative bis(mexylamino)triazines were studied by rheology to establish correlations between their rheological properties and their molecular structure, and all compounds were found to behave in a similar fashion except for the temperature at which glass transition takes place. FTIR and NMR spectroscopy experiments were performed on the molecular glasses studied herein; comparisons between the viscosity, T(g), hydrogen bonding, and association constant (K(a)) in CDCl3 solution have revealed a relationship between the rheological properties, the T(g) of the molecular glasses, and the extent and strength of hydrogen bonding present in the material.
This paper presents a cost- and time-effective wearable inertial sensor system, the InertialLAB. It includes gyroscopes and accelerometers for the real-time monitoring of 3D-angular velocity and 3D-acceleration of up to six lower limbs and trunk segment and sagittal joint angle up to six joints. InertialLAB followed an open architecture with a low computational load to be executed by wearable processing units up to 200 Hz for fostering kinematic gait data to third-party systems, advancing similar commercial systems. For joint angle estimation, we developed a trigonometric method based on the segments’ orientation previously computed by fusion-based methods. The validation covered healthy gait patterns in varying speed and terrain (flat, ramp, and stairs) and including turns, extending the experiments approached in the literature. The benchmarking analysis to MVN BIOMECH reported that InertialLAB provides more reliable measures in stairs than in flat terrain and ramp. The joint angle time-series of InertialLAB showed good waveform similarity (>0.898) with MVN BIOMECH, resulting in high reliability and excellent validity. User-independent neural network regression models successfully minimized the drift errors observed in InertialLAB’s joint angles (NRMSE < 0.092). Further, users ranked InertialLAB as good in terms of usability. InertialLAB shows promise for daily kinematic gait analysis and real-time kinematic feedback for wearable third-party systems.
More versatile, user-independent tools for recognizing and predicting locomotion modes (LMs) and LM transitions (LMTs) in natural gaits are still needed. This study tackles these challenges by proposing an automatic, user-independent recognition and prediction tool using easily wearable kinematic motion sensors for innovatively classifying several LMs (walking direction, level-ground walking, ascend and descend stairs, and ascend and descend ramps) and respective LMTs. We compared diverse state-of-theart feature processing and dimensionality reduction methods and machine-learning classifiers to find an effective tool for recognition and prediction of LMs and LMTs. The comparison included kinematic patterns from 10 able-bodied subjects. The more accurate tools were achieved using min-max scaling [−1; 1] interval and ''mRMR plus forward selection'' algorithm for feature normalization and dimensionality reduction, respectively, and Gaussian support vector machine classifier. The developed tool was accurate in the recognition (accuracy >99% and >96%) and prediction (accuracy >99% and >93%) of daily LMs and LMTs, respectively, using exclusively kinematic data. The use of kinematic data yielded an effective recognition and prediction tool, predicting the LMs and LMTs one-step-ahead. This timely prediction is relevant for assistive devices providing personalized assistance in daily scenarios. The kinematic data-based machine learning tool innovatively addresses several LMs and LMTs while allowing the user to self-select the leading limb to perform LMTs, ensuring a natural gait.
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