The use of cognitive-behavior therapy (CBT) in addition to antipsychotic regimen to treat persistent psychotic symptoms of schizophrenia is growing. The aim of this study was to compare the efficacy of CBT to a befriending (BF) control group in patients with schizophrenia who are refractory to clozapine. Twenty-one patients completed the 21-week trial. In comparison with the control group, the CBT group showed a significant improvement in the General Psychopathology and total score of the Positive and Negative Syndrome Scale, as well as an improvement of Quality of Life scale. The improvement in psychopathology persisted at 6-month follow-up assessment.

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A terapia analítico-comportamental de uma mulher de 35 anos, cujo caso foi anteriormente publicado estritamente em termos de seus aspectos psiquiátricos, é agora abordada com relação aos determinantes encontrados na história de vida da fobia de deglutição e de outras respostas da mesma classe funcional, todas envolvendo a esquiva experiencial. A psicoeducação envolveu uma detalhada análise funcional da fobia de deglutição e dos problemas de relacionamento, correlacionando numa única perspectiva ambos os fenômenos. A teoria dos quadros relacionais oferece uma possível explicação para o fato de que a cliente promoveu uma extensa e progressiva mudança no padrão alimentar e no relacionamento com pessoas significativas, após unicamente uma série de sessões de exposição gradual, com a presença do terapeuta, a diferentes grupos de alimentos, num delineamento de linha de base múltipla.

Background: Social dysfunction is an important outcome for schizophrenia and can be measured by the evaluation of social skills. Objectives: To compare social skills in patients with schizophrenia classified according the degree of treatment response and severity of psychopathology with normative controls by using the Del Prette Social Skills Inventory (SSI). Methods: Cross-sectional study where the 38 questions SSI was applied to 62 outpatients with schizophrenia and compared with data of 99 normal controls from the general population. The SSI was evaluated by five domains. Psychopathology was measured by the Positive and Negative Syndrome Scale (PANSS). Patients were classified as Treatment Resistant (TRS) and Non Treatment Resistant (NTRS) by the International Psychopharmacology Algorithm Project (IPAP) criteria. ANCOVA was used to control for demographic differences between populations. Results: Patients showed significantly more impaired than controls except for aggressiveness control. When variables such as age, age of onset, schooling or medication dose entered as covariates, differences between controls and patients, or TRS with NTRS, almost disappeared. The SSI and PANSS showed an inverse relationship between their domains. Discussion: The SSI may represent a useful tool for evaluation of social skills in schizophrenia. Antipsychotics may exert a protective effect on social skills.