Introduction: The anabolic-androgenic steroids (AAS) are male sex hormones, developers and maintainers of sexual characteristics associated with masculinity and the anabolic status of somatic tissues. The physical and mental effects of AAS abuse are rare and it is practically impossible to say with certainty what adverse effects may become evident after self-administration, but they constitute risk of death for individuals. Objective: The aim of this study was to describe the main characteristics of morbidity due to AAS intake in Brazil, in the period 2000/2010. Methods: Information on hospitalizations was obtained from computerized databases of the Ministry of Health. In the analysis of the consumption of AAS as primary or secondary diagnosis, the codes E28.1 (androgen excess), E34.5 (androgen insensitivity syndrome), T38.7 (adverse effect of and underdosing of androgens and anabolic congeners) and Y42.7 (adverse effects in the therapeutic use of androgens and anabolic congeners) of the ICD-10 were used. Results: Hospitalizations due to AAS were responsible for 0.001% of total admissions in the country. 1,319 admissions (mean = 119.9, SD = 99.01) were counted. The Androgen insensitivity syndrome was the primary cause, corresponding to 55.8% of total admissions. Out of all hospitalizations, 1% of patients died and the longest stay was of 47 days (mean = 3.8, SD = 4.7). Minas Gerais, Maranhão and Espírito Santo present the highest rates of hospital admissions per 1,000,000 inhabitants between the years 2002 and 2007. Women and individuals aged 15-29 presented higher hospitalization rate, 82.5% and 37.7%, respectively. Conclusion: The results of this study showed that the rate of hospitalization was relatively low for AAS intake. Women and individuals aged 15-29 years presented the highest rates in the period studied.
Results show that major neonatal outcomes are very similar between multiples and singletons births when paired by gestational age and birth weight. NEC remained a significant morbidity in infants born from multiple gestations after adjustment for maternal and neonatal risk factors.
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