Lung cancer is one of the major cause for high‐death rate all over the world, due to increased metastasize and difficulties in diagnosis. Naringenin is naturally occurring flavonoid found in various fruits including tomatoes, citrus fruit and figs. Naringenin is known to have several therapeutic effects including anti‐atherogenic, antimicrobial, anti‐inflammatory, hepatoprotective, anticancer and anti‐mutagenic. The present study was aimed to analyse the naringenin induced anti‐proliferative and apoptosis effects in human lung cancer cells. Cells were treated with various concentrations of naringenin (10, 100 & 200 µmol/L) for 48 hours. Cisplatin (20 µg/mL) was used as positive control. Cell viability, apoptosis, migration and mRNA, and protein expression of caspase‐3, matrixmetallo proteinases‐2 (MMP‐2) and MMP‐9 were determined. The cell viability was 93.7 ± 7.5, 51.4 ± 4.4 and 32.1 ± 2.1 at 10, 100 and 200 µmol/L of naringenin respectively. Naringenin significantly increased apoptotic cells. The 100 and 200 µmol/L of naringenin significantly suppressed the larger wounds of cultured human cancer cells compared with the untreated lung cancer cells. Naringenin increased d the expression of caspase‐3 and reduced the expression of MMP‐2 and MMP‐9. Taking all these data together, it is suggested that the naringenin was effective against human lung cancer proliferation, migration and metastasis.
Stable interfaces between immiscible solvents are crucial for chemical synthesis and assembly, but interfaces between miscible solvents have been less explored. Here the authors report the spontaneous water-on-water spreading and self-assembly of polyelectrolyte membranes. An aqueous mixture solution containing poly(ethyleneimine) and poly(sodium 4-styrenesulfonate) spreads efficiently on acidic water, leading to the formation of hierarchically porous membranes. The reduced surface tension of the polyelectrolyte mixture solution drives the surface spreading, while the interfacial polyelectrolytes complexation triggered by the low pH of water mitigates water-in-water mixing. The synergy of surface tension and pH-dependent complexation represents a generic mechanism governing interfaces between miscible solvents for materials engineering, without the need for surfactants or sophisticated equipment. As a proof-of-concept, porous polyelectrolyte hybrid membranes are prepared by surface spreading, exhibiting exceptional solar thermal evaporation performance (2.8 kg/m2h) under 1-sun irradiation.
A new electrolyte based on fluorinated 3-(1,1,2,2-tetrafluoroethoxy)-1,1,2,2-tetrafluoropropane (F-EPE) solvent is developed to decrease the capacity fading of LiNi 1/3 Co 1/3 Mn 1/3 O 2 /graphite lithium-ion batteries (LIBs) cycled in the voltage range of 3.0-4.5 V (vs. Li/Li + ). The linear sweep voltammetry (LSV) and cyclic voltammetry (CV) indicate that F-EPE has an oxidation potential of more than 5.4 V vs. Li/Li + , which is higher than traditional solvents and enlarges the oxidative window of electrolyte. Especially, compared with the LiNi 1/3 Co 1/3 Mn 1/3 O 2 /graphite cells without F-EPE in the electrolyte, the capacity retentions of the cells contained 20 wt% F-EPE and cycled in 3.0-4.5 V are significantly increased from 12.3% to 85.0% after 100 cycles. In addition, the cathode and the anode are respectively characterized in three-electrode systems by electrochemical impedance spectrum (EIS), scanning electron microscope (SEM), energy dispersive spectrometer (EDS), and transmission electron microscopy (TEM) to elaborate the reaction mechanism of F-EPE in the cells. The enhanced performances can be ascribed to that F-EPE cannot only greatly improve the oxidation stability of electrolyte solutions but also participate in the formation of passivation film on the graphite anode, indicating the positive effect of F-EPE on the performances of LIBs cycled in 3.0-4.5 V.) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 10.220.39.223 Downloaded on 2015-07-27 to IP ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 10.220.39.223 Downloaded on 2015-07-27 to IP ) unless CC License in place (see abstract). ecsdl.org/site/terms_use address. Redistribution subject to ECS terms of use (see 10.220.39.223 Downloaded on 2015-07-27 to IP
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