The aim of this study was to test the accuracy of two methods for age estimation in non-adults, Cameriere's European formula and AlQahtani's London Atlas, on a multiethnic American sample. Radiographs of European, Hispanic and American Indian children (166 girls and 194 boys) aged between 6 and 17 years were analyzed following both methods. The accuracy of each method was assessed using the mean difference and the mean of the absolute values of the residuals (mean prediction error). Categories relating to ethnicity, sex and age were applied to the assessment of accuracy in order to compare these two approaches. Results indicate that Cameriere's European formula significantly underestimated age for both sexes (p < 0.001), with a mean difference of -