Objectives: The objective of the study is to assess the retinal redetachment after early and late removal of silicone oil. Place and Duration of Study: Department of ophthalmology eye unit 3, KEMU /Mayo hospital, Lahore from February 2021 to July 2021 . Study: Quasi experimental trial. Patients and Methods: Time of silicone oil removal of first group (29 patients) at 6 weeks and second group (29 patients) at 12 weeks post-operatively. Presence of 360 barrage laser. The two groups were compared as to the condition of the eye at the time of SOR at 1st day 1st week, 1st months.3rd month following SOR. Inclusion Criteria PPV for rhegemantogenous RD with all types of breaks with silicon oil tamponade, both gender 360 barrage laser. Exclusion criteria bands keratopathy grade c PVR, presence of cataract, GRT, only eye Results: The risk of retinal re-detachment was similar in both groups. Conclusion: The danger of re-detachment was not increased by early removal of silicone oil after six weeks, and higher compliance with the removal period was ensured. In patients who are less likely to follow a procedure for delayed removal, it is especially advised..
Purpose: To determine frequency of post-operative macular edema in diabetic retinopathy patients having received preoperative intravitreal bevacizumab, after phacoemulsification cataract surgery while compared with the controls. Study Design: Quasi experimental trial Place and Duration of Study: Department of ophthalmology eye unit 3, KEMU /Mayo hospital, Lahore from March 2020 to August 2020. Methods: A total of 60 patients were included in the study and randomly divided into two groups. Patients of study group were given 1.25mg bevacizumab injection by IV route two weeks priority to surgery while nothing was administered in the control group. Before one week of surgery ocular examination and OCT were perfumed and it was repeated after every month of performance of surgery. Allocation of patients was even not known to the researcher to avoid biasness. Components of monthly examination were best correct visual acuity, slit lamp examination and central macular thickness quantification with OCT. Standard cataract surgery was performed in all the patients (phacoemulsification and implantation of monofocal intraocular lens (IOL)). Post-operatively, all patients were given standard treatment i.e moxifloxacin-dexamethasone). Follow up of all the patients was made for consecutive three months on monthly basis to assess outcome variables i.e macular edema was observed keeping in view central macular thickness. Results: In patients of study group, 16.66% had developed macular edema while in control group it was observed in 46% patients. While comparing macular edema between side of eye, study group had 02 (13.33%) patients belonging to right eye while 03(20.0%) had left eye. However, in control group it was 08 (53.33%) and 06 (40.0%) for right and left eyes respectively. Group A had 230.23 ± 32.16 µm central macular thickness while it was 274.21 ± 25.34 µm in group B. Conclusion: In macular edema prophylaxis using preoperative intravitreal bevacizumab is efficacious in comparison with the controls in patients with mild-moderate edema. Keywords: NPDR, Macular edema, Intravitreal Bevacizumab, Phacoemulsification Surgery, Diabetic Retinopathy.
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