No abstract

No abstract

No abstract

Abstract-Microarrays (DNA, protein, etc.) are massively parallel affinity-based biosensors capable of detecting and quantifying a large number of different genomic particles simultaneously. Among them, DNA microarrays comprising tens of thousands of probe spots are currently being employed to test multitude of targets in a single experiment. In conventional microarrays, each spot contains a large number of copies of a single probe designed to capture a single target, and, hence, collects only a single data point. This is a wasteful use of the sensing resources in comparative DNA microarray experiments, where a test sample is measured relative to a reference sample. Typically, only a fraction of the total number of genes represented by the two samples is differentially expressed, and, thus, a vast number of probe spots may not provide any useful information. To this end, we propose an alternative design, the so-called compressed microarrays, wherein each spot contains copies of several different probes and the total number of spots is potentially much smaller than the number of targets being tested. Fewer spots directly translates to significantly lower costs due to cheaper array manufacturing, simpler image acquisition and processing, and smaller amount of genomic material needed for experiments. To recover signals from compressed microarray measurements, we leverage ideas from compressive sampling. For sparse measurement matrices, we propose an algorithm that has significantly lower computational complexity than the widely used linear-programming-based methods, and can also recover signals with less sparsity.

An arbitrary Ising model can be exactly recovered from observations using an information-theoretically optimal amount of data.

The property of spatial mixing and strong spatial mixing in spin systems has been of interest because of its implications on uniqueness of Gibbs measures on infinite graphs and efficient approximation of counting problems that are otherwise known to be #P hard. In the context of coloring, strong spatial mixing has been established for regular trees in [GS11] when q ≥ α * ∆ + 1 where q the number of colors, ∆ is the degree and α * = 1.763.. is the unique solution to xe −1/x = 1. It has also been established in [GMP05] for bounded degree lattice graphs whenever q ≥ α * ∆ − β for some constant β, where ∆ is the maximum vertex degree of the graph. The latter uses a technique based on recursively constructed coupling of Markov chains whereas the former is based on establishing decay of correlations on the tree. We establish strong spatial mixing of list colorings on arbitrary bounded degree triangle-free graphs whenever the size of the list of each vertex v is at least α∆(v)+ β where ∆(v) is the degree of vertex v and α > α * and β is a constant that only depends on α. We do this by proving the decay of correlations via recursive contraction of the distance between the marginals measured with respect to a suitably chosen error function.

The optimal power flow problem plays an important role in the market clearing and operation of electric power systems. However, with increasing uncertainty from renewable energy operation, the optimal operating point of the system changes more significantly in real-time. In this paper, we aim at developing control policies that are able to track the optimal set-point with high probability. The approach is based on the observation that the OPF solution corresponding to a certain uncertainty realization is a basic feasible solution, which provides an affine control policy. The optimality of this basis policy is restricted to uncertainty realizations that share the same set of active constraints. We propose an ensemble control policy that combines several basis policies to improve performance. Although the number of possible bases is exponential in the size of the system, we show that only a few of them are relevant to system operation. We adopt a statistical learning approach to learn these important bases, and provide theoretical results that validate our observations. For most systems, we observe that efficient ensemble policies constructed using as few as ten bases, are able to obtain optimal solutions with high probability.

Abstract-Natural gas transmission pipelines are complex systems whose flow characteristics are governed by challenging nonlinear physical behavior. These pipelines extend over hundreds and even thousands of miles. Gas is typically injected into the system at a constant rate, and a series of compressors are distributed along the pipeline to boost the gas pressure to maintain system pressure and throughput. These compressors consume a portion of the gas, and one goal of the operator is to control the compressor operation to minimize this consumption while satisfying pressure constraints at the gas load points. The optimization of these operations is computationally challenging. Many pipelines simply rely on the intuition and prior experience of operators to make these decisions. Here, we present a new geometric programming approach for optimizing compressor operation in natural gas pipelines. Using models of real natural gas pipelines, we show that the geometric programming algorithm consistently outperforms approaches that mimic existing state of practice.