Introduction: A retrospective analysis of all poisoning cases admitted to Al-Ameen Medical College, Vijayapura, Karnataka from Jan 2015 to Dec 2015 was done to study the pattern of poisoning. Acute poisoning is one of the important causes of morbidity and mortality in developing countries due to easy availability of poisonous substances and its low cost. So it was important to know the pattern of poisoning at to Al-Ameen Medical College, Vijayapura. Material & methods:A retrospective analysis of all poisoning cases admitted to Al-Ameen Medical College, Vijayapura, Karnataka from Jan 2015 to Dec 2015 was done to study the pattern of poisoning. Objective of the study was to know the socio-demographic profile of the poisoning cases. Data collected using a pretested proforma and the values were analyzed and presented. Results: A total of 211 patients (male: 131, female: 80) studied. The age of the patients varied from 9-71 years. In more than 25 years of age, there was male predominance in all the age group. The types of poisons were insecticides like Insecticides, Alcohol, Kerosene, Rat poison, Phenol, Lice Powder, Turpentine, Glass powder and a large proportion included Unknown poison. The hospital stay of the admitted patients with poisoning ranged from 01 to 58 days. The mean hospital stay was 6 days. In the study group mortality was 3%. Conclusion: Intentional poisoning among young adults is a common public health hazardous. The commonest poisoning includes organophosphrous, halogenated insecticides, and petroleum products.
Abstract:Hyperthyroidism presents with a myriad of symptoms and signs, periodic paralysis is rare among them. Thyrotoxic periodic paralysis is a condition in which there are acute episodes of muscle weakness in patients with high levels of thyroid hormones. Hypokalemia is the commonest cause of muscle weakness in this disorder, but potassium (K + ) levels may be normal in between the attacks. Normal K + levels can also be seen in thyrotoxic normokalemic periodic paralysis where K + levels are normal even during the paralysis. A patient presenting with paralysis as the first presentation in thyrotoxicosis is extremely rare. Here we present a case of twenty one year old male patient presenting with thyrotoxic normokalemic periodic paraplegia as the first presentation.
A 22-year-old female with seven months of amenorrhea presented with chronic headache since the past four months. She has been diagnosed with high blood pressure since the same time. She had a complete spontaneous pregnancy loss at six weeks of gestation, one year back. She also had vasculopathy of distal anterior and posterior tibial arteries which resulted in the obstruction of the arteries and gangrene of first 3 toes of left foot for which she underwent disarticulation [Table/ Fig-1].
Background: Homocysteine has primary atherogenic and prothrombotic properties. The present study aimed to assess serum homocysteine levels in patients with ischemic stroke and to find association of serum homocysteine levels with various patient related variables.Methods: This observational study included patients who were admitted with the diagnosis of stroke in Sri Ventateswara Ramnarain Ruia Government General Hospital. Patients were evaluated for risk factors like hypertension, diabetes mellitus and hyperlipidemia. Total homocysteine estimation was done and survival of the patients was assessed at the time of discharge from the hospital.Results: Most common risk factor for stroke in our study population was dyslipidemia (40%), followed by hypertension (36%). Total homocysteine levels were raised in 92% of the patients. Patients with homocysteine levels less than 15mM/L had lacunar infarcts. Homocysteine levels higher than 100mM/L were found in 18% of the patients and they all had large sized lesions. Significantly higher mean homocysteine levels were found among patients with large lesions (70.15±2.65 vs 21.68±8.02, p value <0.05). Among various risk factors, higher mean homocysteine levels were found to be associated with dyslipidemia (p value <0.05). No association between hypertension, diabetes mellitus or smoking history was found with higher homocysteine levels. Patients who survived had significantly lower homocysteine levels as compared to non survivors (39.3±19.84 vs 100±18.82, p value<0.001).Conclusions: Further studies are needed on homocysteine and stroke fur using homocysteine as screening test and for initiation of preventive therapy of stroke based on homocysteine levels.
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