Purpose: We sought to explore the application value of small-probe endoscopic ultrasonography (EUS) in combination with precut endoscopic mucosal resection (EMR) in the treatment of rectal carcinoids. Methods: Biopsies were performed on patients with rectal submucosal swelling found by colonoscopy at our hospital, and patients whose pathological results were considered indicative of a neuroendocrine tumor were evaluated further. After EUS and computed tomography examinations, patients without peripheral disease or metastasis were treated with precut EMR. Results: Thirty-eight patients were considered to have neuroendocrine tumors by pathological biopsy; of these, 37 patients were treated with precut EMR, and one patient with muscularis propria involvement was treated with surgery. The precut EMR operation time was 28 ± 12 minutes, the whole resection rate was 96.6%, and the complete resection rate was 100%. There were no cases of intraoperative perforation, all of which were located in the rectum. The lesion diameter range was 0.6 to 2.0 cm. There were 10 cases of immediate bleeding during the operation and one case of delayed bleeding after the operation. The length of postoperative follow-up was three to 12 months without recurrence or metastasis. Conclusion: Small-probe ultrasound endoscopy can clarify the depth and diameter of rectal carcinoid invasion, demonstrating a high guiding value for the selection of treatment methods. Precut EMR is a safe, time-saving, and effective method for treating rectal neuroendocrine tumors less than 20 mm in diameter.
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