Developing a facile, cost-saving, and environment-friendly method for fabricating a multifunctional humidity sensor is of great significance to expand its practical applications. However, most humidity sensors involve a complex fabrication process, resulting in their high cost and narrow application fields. Herein, a multifunctional paper-based humidity sensor with many advantages is proposed. This humidity sensor is fabricated using conventional printing paper and flexible conductive adhesive tape by a facile pasting method, in which the paper is used as both the humidity-sensing material and the substrate of the sensor. Owing to the moderate hydrophilicity of the paper and the rational structure design of the paper-based humidity sensor, the sensor exhibits an excellent humidity-sensing response of more than 103 as well as good linearity (R 2 = 0.9549) within the humidity range from 41.1 to 91.5% relative humidity. Furthermore, the paper-based humidity sensor has good flexibility and compatibility, endowing it with multifunctional applications for breath rate, baby diaper wetting, noncontact switch, skin humidity, and spatial localization monitoring. Although the resistance of the paper-based humidity sensor is relatively large, the humidity-sensing response signals of the sensor can be conveniently processed by the designed signal processing system. The readily available starting materials and facile fabrication technique provide useful strategies for the development of multifunctional humidity sensors.

Paper, as a flexible, low-cost, lightweight, tailorable, environmental-friendly, degradable, and renewable material, is emerging in electronic devices. Especially, many kinds of paper-based (PB) sensors have been reported for wearable applications in recent years. Among them, the PB gas, humidity, and strain sensors are widely studied for monitoring gas, humidity, and strain from the human body and the environment. However, gas, humidity, and strain often coexist and interact, and the paper itself is hydrophilic and flexible, resulting in that it is still challenging to develop high-performance PB sensors specialized for gas, humidity, and strain detections. Therefore, it is necessary to summarize and discuss them systematically. In this review, we focus on summarizing the state-of-art studies of the PB gas, humidity, and strain sensors. Specifically, the fabrications (electrodes and sensing materials) and applications of PB gas, humidity, and strain sensors are summarized and discussed. The current challenges and the potential trends of PB sensors for gas, humidity, and strain detections are also outlined. This review not only can help readers to understand the development status of the PB gas, humidity, and strain sensors but also is helpful for readers to find out and solve the problems in this field through comparative reading.

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With its unique structure of two compartments, Janus particles inadequate, including to be used as a drug delivery system to deliver multiple payloads with widely different solubility. Here we report on a fluidic nanoprecipitation system (FNPS), capable of fabricating biocompatible Janus polymeric nanoparticles comprised of the FDA-approved polymer poly(lactic-co-glycolic acid) (PLGA). The FNPS contains dual inlets, one for each half of the particle, that insert into the precipitation stream. The system provides a one-step approach for production of Janus polymeric particles with submicrometer diameters and is likely amenable to substantial scale-up. To the best of our knowledge, this is the first demonstration of biocompatible Janus nanoparticles that encapsulate a hydrophobic drug (paclitaxel) on one side and a hydrophilic drug (doxorubicin hydrochloride) on the other.

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