Background: Digitalization of healthcare led to the optimization of monitoring, diagnostics, and treatment of the range of disorders. Taking into account recent situation with COVID-19 pandemics, digital technologies allowed to improve management of viral infections via remote monitoring and diagnostics of infected patients. Up to date, various mobile health applications (apps) have been proposed, including apps for the patients diagnosed with cardiovascular pathologies. Objective: The presented review aimed at the analyses of a range of mHealth solutions used to improve primary cardiac care. In addition, we studied the factors driving and hindering the wide introduction of mHealth services in the clinics. Methods: The work was based on the guidelines of the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement. The publication search was carried out using PubMed, Web of Science, Cochrane Library, Scopus, and Google Scholar databases. Studies published during the period from 2014 until January 2022 were selected for the analysis. The evaluation of risk of bias for the included studies was conducted using the Cochrane Collaboration Risk of Bias tool. Results and Discussion: An overall 5513 studies were assessed for eligibility after which 39 studies were included.. The main trend in the mobile health for cardiological applications is the use of different types of wearable devices and Artificial Intelligence-platforms. In fact, mobile technology allows remotely to monitor, interpret, and analyze biomedical data collected from the patient. Conclusion: The results of this literature search demonstrated that patients diagnosed with cardiovascular disorders can potentially benefit from the application of mHealth in cardiology. However, despite the proven advantages of mHealth for cardiology, there are many challenges and concerns regarding effectiveness, safety, reliability and the lack of official regulation and guidelines from official organizations. Such issues require solutions and further work towards a wide implementation of mHealth technologies in cardiac practice.