Papillon-Lefèvre syndrome (PLS) is a rare disorder characterized by palmar plantar hyperkeratosis and rapidly progressive periodontitis with loss of deciduous and permanent dentition at an early age. It is reported to occur in 1 to 4 individuals per million people. This case report presents highlighting features of the rare PLS in a 17-year old male who complained of discomfort while mastication and it was accompanied with symmetrical, sharply demarcated erythematous plaques involving the skin of the palms and soles, which extended to the finger joints, elbows, and knees. Along with the rough and dry skin, hyperhidrosis of lesion with a foul odor and transverse grooving of nails were noted. The past dental history revealed normal eruption of deciduous teeth followed by pre-mature mobility and shedding in 4-6 months. Permanent teeth also showed normal eruption and early shedding in the next 4-5 years. Complete edentulous maxillary and mandibular arches led to a decrease in alveolar bone and facial heights. There was no similar disorder in the patient’s family but family history revealed the consanguineous marriage of the patient’s parents.
Background: The aim of this study is the effect of stress distribution within the bone with varying implant crest module designs. Materials and Methods: Finite element models of a straight two-piece 4 mm × 13 mm screw-shaped threaded implant with divergent, straight, and convergent implant crest module with their surrounding suprastructure embedded in mandibular second premolar area were created with ANSYS software. Different implant crest module designs incorporated in D2 types of bone under 100N axial and 100N at 20° oblique load were created to evaluate stress distribution in the crestal bone around implant crest module. Results: Maximum von Mises stress was observed at the crestal region of the bone and at crest module region of the implants in all the models. Divergent crest module design shows minimum von Mises stress at crestal bone during vertical loading within bone and at implant crest module. Straight crest module designs result in minimum stresses during oblique loading than vertical loading. Convergent crest module design shows maximum von Mises stress. Conclusion: Within limitations of the study, it was concluded that stress distribution in adjacent compact bone is greatly influenced by implant crest module design. Divergent crest module designs result in minimum stresses at crestal bone and in the implant crest module region, followed by straight and convergent crest module in ascending order of stress distribution.
The synthesis and characterization of an unique tetradentate Schiff bases were presented in this report namely: 2-(4,5dihydro-1,5-diphynyl-1H-pyrazole-3-yl)phenol (HL 1 ) and 2-(4,5dihydro-5-(4-methoxyphenyl)-1-phynyl-1H-pyrazole-3yl)phenol (HL 2 ) and their copper complexes. On the basis of elemental analysis, magnetic susceptibility, conductivity, electronic, IR, ESR spectral data and powder X-ray powder diffraction observations indicated that for investigated complexes have been proposed octahedral geometry. The stability constants were determined using the p H metric technique. At various temperatures, a series of titrations using standard NaOH solution were performed. a temperature of 25°C and 30 0 C. On the basis of experimental results and analysis it is observed that the values of proton-ligand stability constants and metal-ligand stability constants were found to decrease with increase in temperature. The antimicrobial and antifungal activities of the studied ligands as well as their copper complexes were evaluated using the cup plate technique at various doses in DMSO solvent using the minimum inhibitory concentration (MIC) method. The research indicates that Cu(II) complexes have high microbial activity, whereas ligands (HL 1 ) and (HL 2 ) have moderate activity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.