The neuromuscular blocking actions of sisomicin sulfate (SISO), micronomicin sulfate (MCR) and d-tubocurarine (dTc) were studied in 20 rabbits anesthetized with halothane. The i.v. administration of SISO 20-40 mg/kg, MCR 40-80 mg/kg or dTc 0.1-0.3 mg/kg resulted in dose-dependent decreases in twitch tension. The ED50s for SISO, MCR and dTc were 23.5, 58.2 and 0.2 mg/kg, respectively. SISO- and MCR-induced neuromuscular blockade was partially antagonized by neostigmine or by calcium.
In order to form a Ni Al intermetallic compound layer on a carbon steel surface, Atmospheric controlled Induction Heating Fine Particle Peening (AIH FPP) was carried out at 900°C in argon atmosphere with nickel and aluminum particles mechanically milled by planetary ball mills. The treated surface was analyzed using a scanning electron microscope (SEM), an energy dispersive X ray spectrometer (EDX), and an X ray diffraction (XRD). Oxidation tests were carried out at 900°C for 100 hours. Results showed that the Ni Al intermetallic compound layer with a thickness of 200 mm was formed in the case of the specimen treated by the aluminum rich shot particles; the ratio of Ni to Al was 1 to 4 (mol). This was because (i) melted aluminum particles decreased the melting point of nickel particles and the steel substrate, and (ii) partially melted area promoted a combustion synthesis reaction between nickel and aluminum, resulting in forming the Ni Al intermetallic compound layer. The AIH FPP treated surface showed a higher oxidation resistance than that of the un treated specimen. This was because Al 2 O 3 continually created from the Ni Al intermetallic compound layer protected the steel substrate.
In order to form a Ti-Al intermetallic compound layer on a carbon steel surface, an atmospheric-controlled induction heating fine particle peening (AIH-FPP) treatment was performed at 1000℃ in argon atmosphere. The shot particles were prepared by a mechanical milling method. Titanium and aluminum particles at molar ratios of one to three were mechanically milled by a planetary ball mill for 6 h. The treated surface was analyzed using a scanning electron microscope, an energy dispersive X-ray spectrometer and X-ray diffraction. The reciprocating dry wear tests were performed under the following conditions; an opposing material of alumina balls of 3 mm in diameter, a load of 2.0 N, a sliding speed of 600 mm/min and a sliding distance of 224 m. The results showed that a Ti-Al intermetallic compound layer consisting mainly of TiAl 3 formed on the surface of carbon steel by AIH-FPP treatment. This was because the shot particles were transferred to the substrate and the aluminum and titanium in the particles reacted neither excessively nor insufficiently. The AIH-FPP treated surface showed a higher wear resistance than that of the untreated surface. This was because the wear mode of carbon steel changed from abrasive wear to adhesive wear owing to the formation of the Ti-Al intermetallic compound layer on the surface.
The effect of the intermetallic compound layer formed by atmospheric controlled induction heating fine particle peening (AIH-FPP) treatment on the wear resistance and high-temperature oxidation resistance of titanium alloy was investigated. To form an intermetallic compound layer on a titanium alloy by AIH-FPP treatment, pure titanium, aluminum and nickel particles were mechanically milled using a planetary ball mill, and the prepared particles were used as shot particles in the AIH-FPP treatment. The results showed that intermetallic compound layers, consisted of Ti 3 Al and Ti 2 NiAl 3 , were formed on titanium alloy by AIH-FPP treatment using the prepared particles. The wear resistance and high-temperature oxidation resistance of the AIH-FPP treated specimen were higher than those of the untreated ones.
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