Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) will lead to the aggravation of respiratory symptoms and accelerate the progression of the disease. So early pulmonary rehabilitation is essential for patients with AECOPD. We aimed to investigate the effect of sitting and lying Liuzijue in AECOPD patients with non-invasive ventilation.Methods: A total of 80 AECOPD patients with non-invasive ventilation were randomly divided into two groups. The controlled group (CG) (n=40) received AECOPD conventional treatment and nursing, and the sitting and lying Liuzijue exercise group (LG) (n=40) received sitting and lying Liuzijue therapy. Participants in the LG were required to take this training for 3 months, 30 minutes once every morning and evening.Pulmonary function test, 6-minute walking test (6MWT), Modified Medical Research Council Dyspnea Scales (mMRC), and the St George's Respiratory Questionnaire (SGRQ) were evaluated before and after the intervention. Blood gas was measured before treatment, 3 days, and 5 days after treatment. In addition, the length of hospital stay, the duration of non-invasive ventilation, and the frequency of acute exacerbation within 6 months after the intervention were compared.Results: Seventy patients completed the study. The pulmonary function, 6MWT, mMRC scores, SGRQ, and pH, were significantly improved in the LG. Meanwhile, the 6MWT of the CG was improved. The comparison between the groups showed that the improvement of the pulmonary function, 6MWD, mMRC scores, SGRQ, the duration of non-invasive ventilation, and the frequency of acute exacerbation within 6 months of the LG group differed significantly from the CG.Conclusions: Sitting and lying Liuzijue exercise methods significantly improved lung function, exercise endurance, and quality of life in AECOPD patients with non-invasive ventilation.

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Background: The incidence rate of prediabetes is increasing year by year. Prediabetes is a continuous ever fount of diabetes. Diabetes is closely related to intestinal flora imbalance and insulin resistance (IR). Previous studies have proved that Baduanjin can effectively improve the blood glucose and blood lipid of patients, but there is no relevant research on intestinal flora and IR. Therefore, this study focuses on the influence of Baduanjin on intestinal flora of patients with prediabetes, so as to improve the effect of IR, and finally delay or prevent the occurrence of to diabetes mellitus 2 type (T2DM). Methods: This study will recruit 80 patients who meet the diagnostic criteria of prediabetes from Hospital of Chengdu University of traditional Chinese Medicine. Eighty patients will be randomly divided into experimental group and control group, 40 cases in each group. The control group received routine lifestyle intervention, and the experimental group received Baduanjin at least 3 to 5 times a week for a total of 6 months. The researchers monitored the intestinal flora, insulin resistance index, blood glucose, blood lipid, body mass index, and other indicators after 3 months of intervention and 6 months of intervention Discussion: Based on previous studies, intestinal flora is closely related to the occurrence and development of T2DM-IR. Baduanjin can significantly improve the blood glucose and blood lipid of patients with prediabetes, and has a positive effect on the intestinal flora of the elderly and significantly improve the intestinal microecological balance. This study used randomized controlled trial to explore the control method between Baduanjin and conventional lifestyle, in order to further establish the application of Baduanjin in patients with prediabetes. Trial registration: This trial protocol has been approved by the research hospital and registered in China clinical trial registration center on July 6, 2020 (ChiCTR2000034490).

Objective. To investigate the effect of mindfulness training on neurological function and quality of life in patients with type 2 diabetic peripheral neuropathy. Methods. This study selected 120 patients with type 2 diabetic peripheral neuropathy and randomly divided them into three independent subgroups according to different training methods: mindfulness meditation group (MM), aerobic exercise group (AE), and mindfulness combined with aerobic exercise group. (MMAE). The three groups were analyzed for SNCV and MNCV velocities, MAAS and TCSS scores, neurological symptom scores, neurological sign scores, and quality of life. Results. Before treatment, SNCV and MNCV were not significantly significant ( P > 0.05 ), but after treatment, SNCV and MNCV were significantly higher, and the MMAE group changed more significantly ( P < 0.05 ); before treatment, MAAS and TCSS scores were not significant ( P > 0.05 ), but after treatment, MAAS scores were significantly higher, TCSS scores were significantly lower, and more significantly in MMAE; the difference was significant ( P < 0.05 ); before treatment, there was no statistical significance of the neurological signs score ( P > 0.05 ); after treatment, the neurological symptoms score and neurological signs score were significantly reduced, and the changes in the MMAE group were statistically significant ( P < 0.05 ); there was no significant difference in the quality of life score before treatment ( P > 0.05 ), and the quality of life score in the MMAE group was significantly increased ( P < 0.05 ). Conclusion. Mindfulness training combined with aerobic exercise has an ideal therapeutic effect on patients with type 2 diabetic peripheral neuropathy, and has a very important role in improving the neurological function and quality of life of the patients. It is a safe and effective treatment method. Therefore, mindfulness training combined with aerobic exercise is worthy of promotion and application.

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