Microbubbles as traditional ultrasound contrast agents have seen tremendous developments and bio-applications in the past decades. Due to their outstanding performance, advanced microbubbles as a multifunctional platform combining both imaging and therapy have been increasingly attracting attention. Associated with ultrasound-mediated stimuli, targeting drug transportation with high precision can be established and, as a consequence, a synergistic treatment strategy may prevail, which implies a bright perspective for this brand-new technology. This perspective article will summarize the latest developments on the advanced microbubbles, and review their emerging biomedical applications for the vast community of both applied ultrasound and functional ultrasound-based materials.
Thermal transport of graphene occupies a unique place in thermal management of electronic devices, especially for nanosize devices with high-density integration and high dissipated power. The structure of graphene on nanometer scale changes its thermal conductance. Here, the thermal
characters of graphene have been researched by nonequilibrium molecular dynamics simulation (NEMDS) at room temperature. Special attention is focused on the edge type (zigzag or armchair) and nanostructure size dependence of conductivity for heat. The consequences suggest that the thermal
conductivity of zigzag edge has been higher than that of armchair, which is because of the higher phonon group velocities. Furthermore, thermal conductivity shows a rising tendency, when the model is calculated from length of 21.84 nm to 43.78 nm. The result indicates that the thermal property
performs a strong dependence on nanostructure size which is less than phonon mean free path (775 nm). Our research highlights the significance of structure attribute relationships together with providing useful guideline in calculations for nanosize devices thermal management.
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