In precise relative positioning applications, an effective approach to improve the interoperability of GNSS systems is the tightly combining or inter-system double-differencing of observations from the common frequencies that are shared by different constellations. As the BeiDou satellites are currently transmitting a B2 signal at 1207.14 MHz that is identical to the Galileo E5b signal, the inter-system double-differenced observations can also be created between observations from both systems at that particular frequency. In this paper, we will focus on the instantaneous ambiguity resolution performance analysis of tightly combining BeiDou B2 and Galileo E5b observations. The size and stability of phase and code Differential Inter-System Biases (DISBs) between BeiDou B2 and Galileo E5b signals are first investigated, in which the new BeiDou and Galileo satellites launched recently will also be included. Then, first results of the Tightly Combined Model (TCM) with a priori corrected DISBs (TCM_C) are evaluated in comparison to the Loosely Combined Model (LCM) and tightly combined model with unknown DISBs (TCM_F) in an instantaneous approach. It is demonstrated that the instantaneous integer ambiguity resolution performance can be improved using the TCM_C with respect to LCM and TCM_F.
Objectives
Depth of invasion (DOI) is the most important predictor for lymph node metastasis in early‐stage oral cancer. This study aims to investigate the effects of the different classifications of AJCC 7th and 8th on predicting lymph node metastasis and the optimal cutoff point for DOI predicting the lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC).
Materials and methods
We performed a retrospective study in 208 TSCC patients in early T stage without clinical or radiological signs of lymph node metastasis. Those patients were treated with elective neck dissection (END) between April 2019 and December 2020. And the relation between DOI and lymph node metastasis was analyzed.
Results
Metastases were found in 58 of 208 patients (27.88%). Of those 58 patients, the mean DOI was 8.311 mm compared to 5.425 mm in patients without metastases (p < 0.0001). The receiver operating characteristic curve (ROC curve) showed an area under the curve of 0.7066 with the most optimal cutoff point on a DOI of 4.050 mm (sensitivity 86.21%, specificity 52%). Linear regression analysis (1 mm ≤ DOI ≤6 mm) revealed that a DOI ≥ 3.211 mm predicated an incidence of occult lymph node metastasis greater than 20%. Regional metastases were found in 12.82% of patients with DOI ≤ 4.0 mm. Within the entire cohort, 60 cases (28.85%) got upgraded with respect to T stage. No tumor underwent downstaging.
Conclusion
The 8th edition provides better lymph node metastasis prediction for TSCC than the 7th. And DOI is a poor predictor for regional metastasis in patients with early T stage clinically node‐negative TSCC. END in patients with early‐stage TSCC should be performed in patients with DOI ≥ 3.211 mm.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.