PURPOSE: We examined the effects of sweet taste stimulation on pain tolerance threshold (PTT) of oral mucosa in children. SUBJECTS AND METHODS: Subjects comprised 10 children (mean age, 7.3±1.2 years) for whom PTT of oral mucosa was measured 2 min after oral administrations of sucrose or xylitol and water. Sine wave current stimulation (2 kHz, 250 Hz and 5 Hz, SWCS) which can stimulate sensory nerve fiber selectively (Aβ, Aδ and C) was used to measure PTT. RESULTS: Sweet taste stimulation with sucrose or xylitol increased oral mucosa PTT in children, but not in adults. No difference in the increased PTT was seen between sucrose and xylitol. CONCLUSIONS: Oral administration of sucrose and xylitol may potentially relieve pain associated with local anesthetic injections in children. effects of sweet taste stimulation on pain tolerance threshold (PTT) in the oral mucosa. The present study used sine wave current stimulation (SWCS) to test the effect of sweet taste stimulation by oral administration of sucrose and xylitol on PTT in the oral mucosa of children. We obtained similar measurements from adults in order to compare PTT of the oral mucosa with that of children. Subjects and Methods Subjects comprised 10 children between 6 and 9 years old (3 boys, 7 girls; mean age, 7.3±1.2 years) who provided consent and whose parent/guardian provided consent after receiving a sufficient explanation of the study purposes and 10 healthy adults (5 men, 5 women; mean age, 35.6±8.2 years) who gave similar consent. Subjects were orally administered three types of liquids: 0.5 ml of 24% sucrose solution (SS group) as the sweet taste stimulation substance; 0.5 ml of xylitol solution (XS group) at the same concentration as the S solution; and 0.5 ml of water (W group). PTT measurements were taken
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.