Flavor is an expression of olfactory and gustatory sensations experienced through a multitude of chemical processes triggered by molecules. Beyond their key role in defining taste and smell, flavor molecules also regulate metabolic processes with consequences to health. Such molecules present in natural sources have been an integral part of human history with limited success in attempts to create synthetic alternatives. Given their utility in various spheres of life such as food and fragrances, it is valuable to have a repository of flavor molecules, their natural sources, physicochemical properties, and sensory responses. FlavorDB (http://cosylab.iiitd.edu.in/flavordb) comprises of 25,595 flavor molecules representing an array of tastes and odors. Among these 2254 molecules are associated with 936 natural ingredients belonging to 34 categories. The dynamic, user-friendly interface of the resource facilitates exploration of flavor molecules for divergent applications: finding molecules matching a desired flavor or structure; exploring molecules of an ingredient; discovering novel food pairings; finding the molecular essence of food ingredients; associating chemical features with a flavor and more. Data-driven studies based on FlavorDB can pave the way for an improved understanding of flavor mechanisms.

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Objective: To study the histo-morphological spectrum of uterine smooth cell tumors withimmunohistochemical expression of estrogen and progesterone receptor and to compare theirexpression with respect to that of surrounding myometrium. Materials & Methods: The study is conducted at a tertiary care hospital in northern India which included themyomectomy as well as hysterectomy specimens of the smooth muscle cell tumor. This study found th Results: at the majority of leiomyoma tumors express positivity for estrogen and progesterone receptors, with one-third showing moderate expression and the rest showing strong expression. The study concludes that the majority of Conclusion: uterine smooth muscle tumors are benign and hormone receptor expression, particularly ER, may play a crucial role in their development and progression, highlighting the need for further research to improve diagnostic and treatment approaches. Additionally, a decrease in hormone receptor expression was observed as tumors progressed from benign to malignant, but the conclusion is limited due to the small number of tumors demonstrating atypical characteristics