A total of 238 arsenical skin cancers in 153 patients (98 men and 55 women) were histologically studied; 117 patients (76.47%) were older than 50. Of the 238 lesions, 46 were epidermoid carcinoma, 36 basal cell (23 deep and 13 superficial), 139 intraepidermal (18 type B keratoses and 121 classical Bowen's lesions and variants) and 17 combined forms. Clinically, it was often impossible to differentiate superficial basal cell carcinoma, intraepidermal carcinoma and combined forms. Bowen's variants (10 with squamous eddies, 6 with features of seborrheic keratosis and 5 with horn formation) were described and illustrated. The combined forms were mixtures of superficial basal cell carcinoma, Bowen's lesion or its variants and Jadassohn epithelioma, Among the 36 basal cell carcinomas, ten revealed bizarre multinucleated giant cells and nuclear atypicalities, three in deep and seven in superficial. Arsenical keratoses consisted of benign type A and malignant type B (intraepidermal carcinoma). Among the 81 type A keratoses 57 revealed no cell atypicalities and 24 only mild ones. Relationships of Bowen's lesions to keratoses and to invasive and metastasizing carcinomas and of keratoses type A to type B and to epidermoid carcinomas were discussed.

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PFTC is infrequently diagnosed preoperatively or intraoperatively due to its rarity, and has a varied and nonspecific presentation. Only 6.3% of the patients had typical symptoms suggestive of tubal carcinoma. This report may benefit surgeons by providing additional information about the clinicopathologic behavior of PFTC so that patients can be appropriately counseled.

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Electron‐microscopic studies of biopsy specimens obtained from 40 patients with anaplastic nasopharyngeal carcinoma revealed a variety of cytoplasmic organization in the neoplastic cells. Three modal types of tumor cells are described. The cytoplasm of type I, the most undifferentiated, contains a multitude of polyribosomes with a small amount of granular endoplasmic reticulum. Type II is distinguished by the prominence of cytoplasmic filaments, and Type III is characterized by a high density of cytoplasm with the predominance of endoplasmic reticulum and Golgi complex. The origin of the tumor cells is postulated in relation to the fine structure of the various normal epithelia of the nasopharynx. Although there are no consistent structural elements unique for nasopharyngeal carcinoma cells, loss of the polarity of tumor cells—as evidenced by lack of uniformity in the position of cytoplasmic components—and a wide range of diversity of cell size and shape in a given tumor are common features observable with the electron microscope.