The results of this study are the first to suggest that statins may reduce the risk of gastric cancer.

Arsenic has been well documented as the major risk factor for blackfoot disease (BFD), a unique peripheral vascular disease that was endemic to the southwestern coast of Taiwan, where residents consumed high-arsenic artesian well water for more than 50 yr. Chronic arsenic exposure was also reported to be associated with increased mortality attributed to colon cancer. A tap-water supply system was implemented in the early 1960s in the BFD-endemic areas. Artesian well water was no longer used for drinking and cooking after the mid-1970s. The objective of this study was to determine whether colon cancer mortality decreased after the improvement of the drinking-water supply system through elimination of arsenic ingestion from artesian well water. Standardized mortality ratios (SMRs) for colon cancer were calculated for the BFD-endemic area for the years 1971-2006. Results showed that mortality due to colon cancer declined in males, but not in females, gradually after the improvement of drinking-water supply system. Based on the reversibility criterion, the association between arsenic exposure and colon cancer incidence is likely to be causal for males but not females. The possibility that our results may be due to chance should be considered; however, gender-specific differences in arsenic metabolism may be a critical factor.

In spring, windblown dust storms originating in the deserts of Mongolia and China make their way to Taipei city. These occurrences are known as Asian dust storm (ADS) events. The objective of this study was to assess the possible associations of ADS on the hospital asthma admissions of residents in Taipei, Taiwan, during the period 1996-2001. We identified 54 dust storm episodes, which were classified as index days. Daily asthma admissions on the index days were compared with admissions on the comparison days. We selected two comparison days for each index day, 7 days before the index days and 7 days after the index days. The effects of dust storms on asthma admissions were prominent 2 days after the event (8%). However, the association was not statistically significant. There may not have been enough power to detect associations resulting from the inadequate sample size of asthma admissions on ADS events days. However, it seems worthwhile to pay more attention to the ADS events and health in the future.