SummaryCongenital duodenal anomalies like atresia, stenosis and web or diaphragm commonly present in the neonatal age with signs of intestinal obstruction. Duodenal webs can sometimes present in early infancy and very rarely beyond infancy. The authors present a case of congenital duodenal web with a very small central aperture in a 2-year-old child with presenting features of persistent vomiting and resultant failure to thrive without any overt signs of intestinal obstruction.
Medical text books have taught us evaluation and diagnosis of disease based on patients' symptoms, signs and relevant investigations and treatment is then implemented according to the clinical condition and current best available evidence. There are objective scoring scales to assess the severity of the condition, progress and eventual outcome. These scales rarely if ever consider the impact of social factors on the course of treatment and eventual clinical outcome. But in a country like India with diverse cultural backgrounds and deep social structures social, cultural and economic factors have great ramifications on the clinical course, treatment and ultimate outcome. Diverse beliefs, faiths, social norms and cultural practices not only have a direct effect on a person's daily life but indirectly also effect educational, professional and health care access. The effects of these factors on families and their way of deciding on their child's management in complex systems show multifaceted dynamic interactions leading to at times unexpected outcomes.
BCG adenitis, the enlargement of regional lymph nodes after BCG vaccination is one of the common complications seen. BCG adenitis may present at varied time interval after the vaccine administration. Different medical and surgical treatment modalities have been reported for its management. We report our management experience of BCG adenitis seen over a period of 1 year.
The ever‐increasing complexity of environmental pollutants urgently warrants the development of new detection technologies. Sensors based on the optical properties of hydrogels enabling fast and easy in situ detection are attracting increasing attention. In this paper, the data from 138 papers about different optical hydrogels (OHs) are extracted for statistical analysis. The detection performance and potential of various types of OHs in different environmental pollutant detection scenarios were evaluated and compared to those obtained using the standard detection method. Based on this analysis, the target recognition and sensing mechanisms of two main types of OHs are reviewed and discussed: photonic crystal hydrogels (PCHs) and fluorescent hydrogels (FHs). For PCHs, the environmental stimulus response, target receptors, inverse opal structures, and molecular imprinting techniques related to PCHs are reviewed and summarized. Furthermore, the different types of fluorophores (i.e., compound probes, biomacromolecules, quantum dots, and luminescent microbes) of FHs are discussed. Finally, the potential academic research directions to address the challenges of applying and developing OHs in environmental sensing are proposed, including the fusion of various OHs, introduction of the latest technologies in various fields to the construction of OHs, and development of multifunctional sensor arrays.
The ever-increasing complexity of environmental pollutants urgently
warrants the development of new detection technologies. In this context,
sensors based on the optical properties of hydrogels enabling fast and
easy in situ detection are attracting increasing attention. Herein, the
target recognition and sensing mechanisms of two main types of optical
hydrogels (OHs) are reviewed and discussed: photonic crystal hydrogels
(PCHs) and fluorescent hydrogels (FHs). For PCHs, the environmental
stimulus response, target receptors, inverse opal structures, and
molecular imprinting techniques related to PCHs are reviewed and
summarized. Furthermore, the different types of fluorophores (i.e.,
compound probes, biomacromolecules, quantum dots, and luminescent
microbes) of FHs are summarized. Finally, the data from 138 papers about
different OHs are extracted for secondary statistical analysis. The
detection performance and potential of various OH types in different
environmental pollutant detection scenarios are evaluated, and compared
them to those obtained using the standard detection method. Based on
this analysis, some possible development directions are proposed,
including the fusion of various OHs, introduction of more hydrogel
technologies from the biomedical field to the environmental pollutant
detection field, and development of multifunctional sensor arrays.
Death following a chronic and complicated illness in hospital is common. This paper is an account of a physician who perceives such a death in a different and an introspective way hoping to make all stakeholders of health realise their responsibilities beyond the accepted norms. There is need for professionalism and patient centredness in healthcare delivery as is stressed in this narrative. Physicians have an added role of teaching medical students and resident doctors and are reminded that they unknowingly transmit their professional identity onto the learners by the manner in which they deal with patients.
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