Aneurysmal bone cysts are blood-filled lesions of the bone that are benign, expansile, aggressive, and locally damaging. They havean atypical presentation and an unknown etiology. We present the case of a 17-year-old male youngster who appeared with a historyof trauma that resulted in a pathological left femur fracture. A subtrochanteric fracture complicated a slowly forming aneurysmalbone cyst in the proximal femur. Excision of the tumor with curettage and open reduction with internal fixation with a titanium elasticnail were successful treatments, and the empty space was replaced with bone graft from the left iliac crest. The gold standard fordiagnosis is a biopsy. Bone grafting should be used in conjunction with fracture fixation to achieve bony union.
Giant cell tumour of the bone is a regionally assertive neoplasm that is implemented in practice with elongated curettage andtherapeutic interventions, which would be having lesser risk of recurrence. The skeletal tumour is a single, non malignant, butregionally assertive cancer. In the fully grown skeleton, it most frequently affects the epiphysis region of bones. This is mostcommon in the femur, tibia and lower end of radius. Lower end of radius tumour makes up of about 10 percent of overall bonytumours. The obliteration of osseous and cartilages in the proximal distal radius giant cell tumour cells makes salvaging the forearmjoint morphology and feature difficult. Numerous techniques are given, such as wide excision and allograft rebuilding or ulnacentralized control with wrist fusion. We reveal, outcomes of a lower end of radius tumour adequately treated with chemicalcauterization and bone grafting, to retain forearm and hand degree of freedom and supination with better functional recovery.
Congenital pseudoarthrosis is specific kind of non-union that is either present or developing at birth. Though its cause is unknown, it commonly affects people with neurofibromatosis. The most common sites of congenital pseudoarthrosis are the distal portion of the tibia and commonly the fibula of the same leg. Approximately one in 250,000 live pregnancies results in congenital pseudarthrosis of the tibia. A 4-year-old child with a history of his right leg being shorter since, birth and being unable to use it for walking arrived at the orthopaedic outpatient clinic. The patient was managed with resection of the callus and pseudoarthrosis site and the tibia shaft was fixed with low contact dynamic compression locking device. The Ilizarov ring fixator was used and corticotomy was performed at the junction of the proximal and middle tibial shafts in order to lengthen the leg using the distraction osteogenesis principle. The goal of surgical therapy is to achieve pseudoarthrosis bone union while restoring limb alignment in order to lessen the risk of a subsequent fracture and keep bone development and function in the leg. It appears as CPT and is commonly accompanied with distinctive anterolateral bending. The Ilizarov procedure offers patients with CPT a therapeutic choice that is secure, useful and realistic. It can achieve a number of goals, including ankle stability, osteosynthesis and leg-length equality, when compared to alternative therapy methods. The fixation technique using a locking compression plate along with a bone graft improves the treatment of complicated congenital pseudarthrosis of the tibia.
Introduction: Platelet-rich plasma (PRP) an autologous platelet concentration that contains a large quantity of growth factors is being used to treat an increasing number of articular cartilage injuries and degenerative cartilage lesions. The purpose of PRP is to stimulate cartilage regeneration biologically. Materials and Methods: Prospectively enrolled were twelve New Zealand rabbit knees that had received Surgical Phenol Solution-induced osteoarthritis and articular cartilage destruction, followed by platelet-rich plasma therapyassisted cartilage regeneration. The research was carried out at the Datta Meghe Institute of Higher Education and Research in Sawangi's animal laboratory (Meghe). The study lasted three years. Following two weeks of surgical phenol solution damage on day 1, four groups underwent three treatments of autologous PRP therapy. Rabbits were examined by an open cartilage biopsy and histopathological analysis to determine whether cartilage regeneration had occurred at 3 months. Discussion: In terms of tissue morphology, matrix staining, cell distribution, integration of regenerated tissue with subchondral bone, tidemark formation, subchondral bone anomalies and mid/deep zone assessment, group C considerably outperformed groups A and B (P 0.05). Studies on osteoporosis and degenerative cartilaginous tissue have demonstrated that PRP can heal injured tissue. Conclusion: In the current experimental research, PRP's potential as a biological stimulator for cartilage regeneration was assessed.This research aimed to expand the role of PRP in improving wound healing outcomes, with a particular emphasis on its effectiveness for skin regeneration. This research will contribute to standardizing the use of PRP in cartilage healing for better results when applied to humans.
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