Manganese and iron doped cadmium gallate has been synthesized by sol–gel approach. PXRD pattern shows the cubic arrangement of cadmium gallate spinel. Raman spectrum concludes the complete structural analysis of undoped and doped samples. Additionally, morphology and elemental ratio is obtained using FESEM and EDS spectroscopy. Blue indigo and green emission bands are shown in photoluminescence spectra. An excellent antiferromagnetic and ferromagnetic behavior of manganese and iron doped cadmium gallate are shown in the magnetic study. Low band gap of doped samples has made this material as a prominent catalyst for the degradation of methylene blue dye when exposed to UV–visible irradiation.
169 Background: Prostate cancer is the most common cancer in men in the United States. Death in prostate cancer patients is often related to other medical conditions and not prostate cancer itself. Hence, it is important to optimize other co-morbidities, such as hyperlipidemia, hypertension, and cardiovascular diseases in these patients. However, there are numerous studies portraying the ability of statins to increase progression free survival and overall survival of prostate cancer. This has led to significant interest of statins having anti-cancer properties and ultimately improving long term outcomes. Methods: This is a retrospective observational study with chart review of 1,011 patients diagnosed with prostate cancer from 1995 to 2010 in a VA Hospital in San Antonio, Texas. Variables included age at diagnosis, statin use, type of statin (1st, 2nd, or 3rd generation), dose of statin (4 dosage levels), length of statin use, time followed in months (from diagnosis to death or end of study period), death, cause of death, and time to first progressive disease. Progressive disease was defined using PSWG2 guidelines which is PSA increase > / = 25% and at least 2ng/dl above the nadir. The Cox proportional hazards regression model was used to estimate the hazard function, with age, co-morbities and other cancers used as a covariate. End points were death by prostate cancer (56), death by any cancer (140), and death by all causes (484). We also looked at the effects of statins on progression free survival of prostate cancer. Results: The hazard ratio (HR) for use of statins and death by prostate cancer was 0.35, 95% confidence interval (CI): 0.20-0.62 (p = 0.0003), indicating that statin use has a statistically significant positive effect at delaying death by prostate cancer. Death by any cancer was significantly affected by statins with a HR of 0.47, 95% CI: 0.32-0.65 (p < 0.0001). Death by all causes was also affected significantly by statins with a HR of 0.64, 95% CI: 0.53-0.78 (p < 0.0001). Length of statin use, shorter versus longer than 4 years, showed an inverse association with our primary end point with a HR of 0.53, 95% CI: 0.40-0.69 (p < 0.0001). Dose level of statin, fourth level vs 1, 2, and 3, also showed an inverse association with our primary end point with a HR of 0.73, 95% CI: 0.57-0.94 (p = 0.014). Lastly, statin exposure significantly increased progression-free survival with a HR of 0.71, 95% CI: 0.53-0.95 (p < 0.021). Conclusions: It is clear that concomitant statin use increases overall survival in patients with prostate cancer, potentially even having anti-cancer protective effects against mortality. Longer duration of statin use and higher dose levels of statins increase length of overall survival in patients with prostate cancer. As mortality is often not due to prostate cancer, more interestingly, statin exposure is also shown to increase progression-free survival.
Background: Pets seem like perfect companions providing unconditional love without any expectation from owner. Pets can be seen as stress reducer and being looked upon as companions and members of the family. The purpose of this study was to examine the effect of pet ownership on happiness, psychological well-being in pet owners and non-pet owners. Methodology: Data was collected from 100 participants. Data was gathered by means of questionnaires that assessed happiness, psychological well-being. The Ryff scale of psychological well-being and subjective happiness scale have been employed. The data were analyzed by employing mean, SD and t-tests. Results: Results of this study showed that there is significant difference in levels of happiness and psychological well-being experienced by pet owners and non-pet owners.
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