Worldwide, there is a rise in the incidence of dengue infection associated with multiple serotypes. Epidemiological studies have reported a higher incidence of severe dengue in secondary dengue infections. A rapid fall in platelet count associated with an increase in hematocrit above the baseline is one of the warning signs of plasma leakage. This study was undertaken to determine the utility of platelet indices such as mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit in dengue fever cases with thrombocytopenia. A hospital-based crosssectional study was carried out between April and September 2014, among dengue patients with thrombocytopenia using platelet histograms. The study population included all the laboratory confirmed cases of dengue infection with thrombocytopenia admitted at Kasturba Medical College, Manipal, Karnataka during the study period. The blood samples collected from serologically confirmed dengue patients with thrombocytopenia were analyzed using automated analyzer within 2 h of venipuncture. The platelet histograms (MPV, PDW, Plateletcrit) generated by the Beckman Coulter counter LH755 TM and LH780 TM series were assessed in dengue fever cases with thrombocytopenia. The mean platelet volume (MPV) was observed to be 9.01 fL (SD = 0.09). The mean platelet distribution width and median plateletcrit were 17.2% (SD = 0.98) and 0.47 (IQR 0.2-0.8) respectively. None of the study participants presented with bleeding manifestations. The present study revealed no significant changes of platelet parameters in dengue cases with thrombocytopenia.
Introduction: In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan, Hubei Province, China and the World Health Organization declared it as a pandemic on 12 March 2020. The pandemic had devastating repercussions in form of human lives, economy and mental health. Method This article brings in light the experiences, expectations and coping mechanisms of the author during raging 30-days duty in a 250 bedded isolated Covid-19 pneumonia ward. Results While the world stagnated in the walls of their residence, the health care workers, donning the badge of “Duty to serve”, faced a real-time war against the pandemic with sidelines of stigma, discrimination and mental trauma, in their stride with their heads held high. Conclusions The article focuses on helpless, frustrating yet intriguing journey through the experiences encountered in midst of the second wave of the pandemic, ending with a sense of humility, gratitude, resilience and post-traumatic growth.
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