Background:Ultrasonographic findings of gastric carcinoma are varied in different population in different region. Objectives: The purpose of the present study was to see the different ultrasonographic findings of stomach cancer patients attended at a tertiary care hospital in Dhaka city. Methodology: This crosssectional study was carried in the department of Radiology and Imaging of Dhaka Medical College, Dhaka during July 2009 to June 2011for a period of 2(two) years. Clinically suspected gastric carcinoma patients were evaluated by ultrasonography of upper abdomen and or Barium-meal x-ray evaluation. The sonographic findings were noted. Biopsy was performed by endoscopy or by surgical resection to confirm the case. Result: A total number of 60 gastric carcinoma patients were recruited.In all 24 patients of gastric carcinoma (100%) wall layering was completely lost. Wall thickness was increased in all the 24 cases (100%). Patients with gastric carcinoma had a wall thickness ranging from 10mm to 38mm with an average wall thickness of 24.5 mm. There was luminal narrowing and reduced peristalsis seen in all the 24 cases. Heterogeneous intraluminal masses were seen in 20 out of 24 (83.33%) cases of gastric carcinoma. Serosal involvement was seen in 17 out of 23 (70.83%) cases. Conclusion: Ultrasonography of gastric carcinoma shows completely lost of wall layering of stomach with increased thickness of it.
Background: Leaf extract of Catharanthus roseus has medicinal effect. Objective: The purpose of the present study was to compare the effect of leaf extract of Catharanthus roseus (Nayantara) with atorvastatin on serum lipid profile in fat-fed rats. Methodology: This was an experimental animal study carried out in the Department of Pharmacology and Therapeutics at Dhaka Medical College, Dhaka from July 2005 to June 2006 for a period of one year. Adult Long Evans rats of both sexes were used for the study. The rats were divided into seven groups designed as A, B, C, D, E, F and G. Each group was comprised of 8 rats which were treated for 10 days and were sacrificed on 11th day. The experiment were designed to demonstrate the effect of C. roseus on serum lipid profile in hyperlipidaemic rats and the hypolipidaemic effects were compared to a standard oral lipid lowering drug, atorvastatin. Result: A total number of 56 adult Long Evans rats of both sexes were used for the study. Here the effect of leaf extract of C. roseus at different doses on lipid level of fat-fed rats was observed which were compared with the hyperlipidaemic control group. In the same time the effect of Atorvastatin on serum lipid level were observed. The observed lipid lowering effect of leaf extract of C. roseus was evaluated biochemically by significant (p<0.001) decrease of serum total cholesterol (TCL), triglyceride (TG) and low density lipoprotein (LDL) levels. The leaf extract of C. roseus was given at three different doses daily in oral route for 10 days along with fatty diet and statistically significant (p<0.05) decrease was observed in all serum lipid parameter (TCL,TG, LDL) except high density lipoprotein (HDL). Which was more evident in higher doses treated group (1 ml/kg and 1.5 ml/kg). Atorvastatin reduced all three parameter (TCL, TG, &LDL) significantly (p<0.001). It increased HDL significantly high (p<0.001). Conclusion: The leaf extract of C. roseus is responsible for lipid lowering effect. [Journal of National Institute of Neurosciences Bangladesh, 2015;1(2): [53][54][55][56]
(01) year. Clinically suspected women with breast mass who were attended in the OPD or inpatient department were selected purposively as study population. All the patients were examined by 2-D Real-Time B-Mode Ultrasonography by using high frequency (7.5 MHz) linear transducer. Blood flow was studied using Duplex sonography in which Gray scale 2D sonography was combined with Pulsed Doppler. Test of validity was done for color Doppler Sonographic findings in evaluation of benign and malignant breast lesion. Result:A total number of 50 cases were recruited for this study. Out of 50 cases,25 cases true positive, 1 false negative, 2 false positive, 22 true negative confirmed by histopathology. Here sensitivity and specificity of color Doppler ultrasonography are 92.59% and 86.95% respectively. Here accuracy of color Doppler study is 90.0% and the positive predictive value was 89.28% and negative predictive value was 90.9%. Conclusion: Color Doppler Ultrasonography is a useful imaging method in the differentiation between benign and malignant breast masses. [Journal of National Institute of Neurosciences Bangladesh, 2017;3(1): 10-13]
Background: Gray scale sonography is an important diagnostic tool for the detection of malignant breast tumour. Objective: The purpose of the present study was to find out the diagnostic validity gray scale sonography to detect malignant lesions of breast. Methodology: This cross-sectional study was carried out in the department of Radiology and Imaging, in collaboration with the department of Surgery and Pathology at Banghabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from July 2008 to June 2009 for a period of one year. Women presented with clinically suspected breast mass from outpatients' department (OPD) or inpatient department (IPD) were purposively selected and was Ultrasonographic diagnosis. 2-D Real-Time B-Mode Ultrasonographic examinations were done using high frequency (7.5 MHz) linear transducer. Result: Test of validity was done for color Doppler Sonographic findings in evaluation of benign and malignant breast lesion. Out of 50 cases, 23 cases were true positive; 4 cases were false negative; 1 case was false positive; 22 cases were true negative confirmed by histopathology. Here sensitivity and specificity of Gray scale ultrasonography were 85.18% and 95.0% respectively. Here accuracy of Gray scale study was 90.0%. Positive predictive value was 95.83% and negative predictive value was 84.61%. Conclusion: Gray scale ultrasonography is a useful method in the differentiation between benign and malignant breast masses.
Background: Intussusception in adult patients is occurred in different reasons. Objectives: The purpose of the present study was to see the spectrum of etiology among adult intussusception patients. Methodology: This case series was performed in the Department of Surgery at Shaheed Suhrawardy Medical College, Dhaka from July 2014 to June 2015 for a period of 1(one) year. All the patients presented with intussusceptions were selected as study population. A detailed history was obtained from each patient. Patients with the age of ≥18 years, regardless the symptoms like onset, duration, intensity, progression were included for this study. Per-operative diagnosis was further confirmed by histopathology of the resected specimen. Result: A total number of 11 cases were recruited after fulfilling the inclusion and exclusion criteria. Gastro intestinal stromal tumour (GIST) was the most common etiology of intussusceptions which was 5(45.5%) cases followed by adenocarcinoma which was 2(18.2%) cases. Meckel"s diverticulum, Intestinal TB, Lipoma and Leiyomyomatous polyp were also found in 1 case each. Conclusion: Adult intussusception is most commonly occurred due to gastro intestinal stromal tumour followed by adenocarcinoma.
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