No abstract

No abstract

No abstract

No abstract

No abstract

coated onto the sample from toluene solution. The average film thickness as determined from optical density measurements is 460 20 nm.For optical pumping of the laser structure we frequency double the output of a regeneratively amplified femtosecond Ti:Sapphire laser. The resulting pulses of 130 fs duration and a wavelength of 400 nm have pulse energies of 0.6 nJ to 10 nJ at a repetition rate of 1 kHz. The excitation beam is focused onto a spot with a diameter of 70 5 lm. The sample is kept under a dynamic vacuum of 10 ±4 mbar and the emission is collected in reflection geometry, dispersed by a grating spectrometer and detected by a charge coupled device (CCD) array.

A controlled drug release system was designed based on the combination of three advantages into one entity, which was composed of Fe 3 O 4 magnetic nanoparticle as the core, mesoporous silica as the sandwiched layer, and thermo-sensitive P(NIPAM-co-NHMA) copolymer as the outer shell. The hydrophilic comonomer content affected the volume phase-transition temperature (VPTT) of this composite microsphere and the behavior of the temperature-triggered drug release. Zn(II) phthalocyanine tetrasulfonic acid (ZnPcS 4 ), a well-known photodynamic therapy (PDT) drug, was used as a model drug to assess the release system. The results demonstrated that the drug release behavior was dependent on the temperature and had a close correlation with the VPTT. Above the VPTT, the drug release rate was much faster than that below the VPTT, which showed a great potential application in tumor therapy.

No abstract