The first synthesis
of benzyne-derived stable zwitterions is reported.
Benzynes generated in situ from 2-(trimethylsilyl)aryl
triflates undergo a multicomponent reaction with phosphines and CO2 to produce the stable 1,5-zwitterionic species in moderate
to excellent isolated yields, which provides a novel method for the
preparation of phosphonium inner salts under mild and transition-metal-free
conditions.
An organic superbase-catalyzed aminocarbonylation reaction of α,β-unsaturated ketones was reported. Under the catalysis of 10 mol% Schwesinger’s superbase t-Bu-P4, a variety of enones and ynone reacted with N, N-dimethyl carbamoylsilane...
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