Recently, metabolic syndrome (MetS) has become an important public health problem, and its prevalence is increasing. MetS is associated with multifactorial diseases. No reports have suggested a relationship between bladder cancer and high blood pressure, and hyperlipidemia has been reported as a possible risk factor. In the present study, we investigated the relationships between the stage and degree of malignancy of bladder cancer and MetS. Furthermore, we investigated the influence of the components of MetS on the results. We retrospectively analyzed the data of 169 patients who underwent transurethral resection of a bladder tumor in our department between Janurary 2005 and March 2011. MetS was significantly associated with a high histological grade (p < 0.05). MetS and low high-density lipo-protein were found to be significantly associated with the T stage; no other components of MetS were associated with a high stage or grade. Our results demonstrated that a lack of therapy for patients with low high-density lipoprotein levels could be riskier than was previously thought.
This report presented the case of an 83-year-old male with penile cancer detected accidently during circumcision for the purpose of facilitating the insertion of resecting scope for bladder carcinoma. This penile cancer was too close to collum glandis to be removed with a sufficient surgical safety margin. After due consideration, we performed the circumcision only 2 mm away from the tumor. The pathological examination of the bladder tumor revealed urothelial carcinoma, G2, pTa, and that of the penile tumor revealed SCC, pTaN0M0. We performed a punch out biopsy at six points around the surgical margin at one week postoperatively. However, we did not detect any malignant tissue in the biopsy specimen. This patient did not want additional postoperative treatment, and was followed-up this patient without treatment. This patient is still alive with no recurrence of any tumor at 1 year after the operation.
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