Cross-laminated timber (CLT) has gained popularity worldwide in recent years, and its use in buildings and civil engineering structures has attracted attention in Japan. In this study, the life-cycle greenhouse gas (GHG) balance and costs associated with CLT floor slabs were evaluated with respect to small-scale bridge repair as the first instance of the use of CLT in civil engineering projects in Japan. Additionally, waterproofing treatment was applied to CLT slabs, and the potential GHG and cost reduction of CLT in comparison with reinforced concrete (RC) slabs were examined. GHG emissions were the smallest for non-waterproofed CLT slabs and the greatest for RC slabs. When replacing RC slabs with CLT slabs without waterproofing, fossil-derived GHG emissions can be reduced by 73 kg-CO2eq/m2 per slab, and fossil/wood-derived GHG emissions can be reduced by 67 kg-CO2eq/m2; however, the use of disposed CLT as fuel is essential. Moreover, a reduction in GHG emissions can be expected if RC slabs are replaced with CLT slabs that are waterproofed only once every 20 years. Further, the cost associated with RC slabs is 20% of that attributable to CLT slabs. Hence, measures need to be taken to reduce the cost of CLT and waterproofing materials.
The aim of this study was to elucidate the lifelong disease progression of chronic obstructive pulmonary disease (COPD) with biomarker changes and identify their influencing factors, by utilizing a new analysis method, Statistical Restoration of Fragmented Time-course (SReFT). Individual patient data (n = 1025) participating in the Study to Understand Mortality and MorbidITy (SUMMIT, NCT01313676), which was collected within the observational period of 4 years, were analyzed. The SReFT analysis suggested that scores of St. George’s Respiratory Questionnaire and COPD assessment test, representative scores of the health-related quality of life (HRQOL) questionnaire, increased consistently for 30 years of disease progression, which was not detected by conventional analysis with a linear mixed effect model. It was estimated by the SReFT analysis that normalized forced expiratory volume in one second for age, sex, and body size (%FEV1) reduced for the initial 10 years from the onset of the disease but thereafter remained constant. The analysis of HRQOL scores and lung functions suggested that smoking cessation slowed COPD progression by approximately half and that exacerbation accelerated it considerably. In conclusion, this retrospective study utilizing SReFT elucidated the progression of COPD over 30 years and associated quantitative changes in the HRQOL scores and lung functions.
Recently, cross-laminated timber (CLT) has attracted attention as a civil engineering material in Japan. In particular, the use of CLT floor slabs for bridge repair is expected to have regional economic impacts throughout their life cycle, but their economic impacts have not been evaluated. In this study, the life cycle regional economic impacts of using non-waterproofed CLT, waterproofed CLT, and reinforced concrete (RC) floor slabs for bridge repair in Akita Prefecture, Japan, were compared. Using past-to-present input–output tables, we quantitatively evaluated the economic impacts over the life cycle of floor slabs by estimating the future input–output tables for construction, maintenance, and disposal. The results showed that the construction and maintenance costs (final demand increase) of CLT floor slabs are higher than those of RC slabs, but the regional economic impact is larger. In addition, the non-waterproofed CLT must be renewed every time it is maintained. Therefore, the demand for CLT production in the prefecture will increase, and the economic impact will be larger than that of the other two floor slabs. This demand for CLT production will not only redound to the benefit of the forestry and wood industry but also the revitalization of regional economies.
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